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Protein

Crossover junction endodeoxyribonuclease RuvC

Gene

M127_5334

Organism
Bacteroides fragilis str. S6L5
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.SAAS annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

Endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction).SAAS annotation

Cofactori

Mg2+SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, NucleaseSAAS annotation
Biological processDNA damage, DNA recombinationSAAS annotation, DNA repairSAAS annotation
LigandMagnesiumSAAS annotation, Metal-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Crossover junction endodeoxyribonuclease RuvCSAAS annotation (EC:3.1.22.4SAAS annotation)
Gene namesi
ORF Names:M127_5334Imported
OrganismiBacteroides fragilis str. S6L5Imported
Taxonomic identifieri1339318 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides
Proteomesi
  • UP000021466 Componenti: Unassembled WGS sequence

Family & Domainsi

Sequence similaritiesi

Belongs to the RuvC family.SAAS annotation

Family and domain databases

Gene3Di3.30.420.10, 1 hit
InterProiView protein in InterPro
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf
IPR020563 X-over_junc_endoDNase_Mg_BS
IPR002176 X-over_junc_endoDNase_RuvC
PANTHERiPTHR30194 PTHR30194, 1 hit
PfamiView protein in Pfam
PF02075 RuvC, 1 hit
PRINTSiPR00696 RSOLVASERUVC
SUPFAMiSSF53098 SSF53098, 1 hit
PROSITEiView protein in PROSITE
PS01321 RUVC, 1 hit

Sequencei

Sequence statusi: Complete.

A0A017PKT4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARGVLLLAA ALRKIPIFEY APSVAKRAVI GKGKASKYQV QLMVSKILHI
60 70
PNILRPDYED IADAFALAIC HAHTSS
Length:76
Mass (Da):8,273
Last modified:June 11, 2014 - v1
Checksum:iC106721C1FACD0EB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JGVC01000076 Genomic DNA Translation: EYE60504.1

Genome annotation databases

EnsemblBacteriaiEYE60504; EYE60504; M127_5334
PATRICifig|1339318.3.peg.571

Similar proteinsi

Entry informationi

Entry nameiA0A017PKT4_BACFG
AccessioniPrimary (citable) accession number: A0A017PKT4
Entry historyiIntegrated into UniProtKB/TrEMBL: June 11, 2014
Last sequence update: June 11, 2014
Last modified: July 18, 2018
This is version 18 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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