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Protein

Ribonuclease 3

Gene

rnc

Organism
Bacteroides fragilis str. Korea 419
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.UniRule annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

Endonucleolytic cleavage to 5'-phosphomonoester.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi62MagnesiumUniRule annotation1
Active sitei66UniRule annotation1
Metal bindingi131MagnesiumUniRule annotation1
Active sitei134UniRule annotation1
Metal bindingi134MagnesiumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonucleaseUniRule annotationSAAS annotation, Hydrolase, Nuclease, RNA-binding, rRNA-bindingUniRule annotationSAAS annotation
Biological processmRNA processingUniRule annotationSAAS annotation, rRNA processingUniRule annotationSAAS annotation, tRNA processingUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease 3UniRule annotation (EC:3.1.26.3UniRule annotation)
Alternative name(s):
Ribonuclease IIIUniRule annotation
Short name:
RNase IIIUniRule annotation
Gene namesi
Name:rncUniRule annotation
ORF Names:M065_0245Imported, M065_0352Imported, M065_0708Imported, M065_0917Imported, M065_1263Imported, M065_5312Imported, M065_5451Imported, M065_6033Imported
OrganismiBacteroides fragilis str. Korea 419Imported
Taxonomic identifieri1339269 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides
Proteomesi
  • UP000021843 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homodimer.UniRule annotationSAAS annotation

Structurei

3D structure databases

SMRiA0A016ENS4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini20 – 145RNase IIIInterPro annotationAdd BLAST126
Domaini173 – 242DRBMInterPro annotationAdd BLAST70

Sequence similaritiesi

Belongs to the ribonuclease III family.SAAS annotation

Family and domain databases

CDDicd00593 RIBOc, 1 hit
Gene3Di1.10.1520.10, 1 hit
HAMAPiMF_00104 RNase_III, 1 hit
InterProiView protein in InterPro
IPR014720 dsRBD_dom
IPR011907 RNase_III
IPR000999 RNase_III_dom
IPR036389 RNase_III_sf
PfamiView protein in Pfam
PF00035 dsrm, 1 hit
PF14622 Ribonucleas_3_3, 1 hit
SMARTiView protein in SMART
SM00358 DSRM, 1 hit
SM00535 RIBOc, 1 hit
SUPFAMiSSF69065 SSF69065, 1 hit
TIGRFAMsiTIGR02191 RNaseIII, 1 hit
PROSITEiView protein in PROSITE
PS50137 DS_RBD, 1 hit
PS00517 RNASE_3_1, 1 hit
PS50142 RNASE_3_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A016ENS4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRNKIDKIR LLFRKDRESY SCFYRILGFY PRNIRLYEQA LLHKSTAVRS
60 70 80 90 100
EKGRPLNNER LEFLGDAILD AIVGDIVYQH FEGKREGFLT NTRSKIVQRE
110 120 130 140 150
TLNKLAVEIG LDKLIKYSTR SSSHNSYMYG NAFEAFIGAI YLDRGYECCK
160 170 180 190 200
QFMERRIIEP YIDLDKLSRK EVNFKSKLIE WSQKNKMEVS FELIEQSLDK
210 220 230 240 250
ENNPVFQTEV RIEGILGGSG TGYSKKESQQ NAAQMTLKKI KGDPEFMASV
260 270 280 290
QEAKTQNNVP AEDTTPESET SLTAENQQID EIISTEEISV
Length:290
Mass (Da):33,486
Last modified:June 11, 2014 - v1
Checksum:iC3A7E6AD5E9B0275
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JGDW01000227 Genomic DNA Translation: EXZ91449.1
JGDW01000159 Genomic DNA Translation: EXZ92185.1
JGDW01000142 Genomic DNA Translation: EXZ92296.1
JGDW01000022 Genomic DNA Translation: EXZ96392.1
JGDW01000021 Genomic DNA Translation: EXZ96497.1
JGDW01000019 Genomic DNA Translation: EXZ96755.1
JGDW01000018 Genomic DNA Translation: EXZ96927.1
JGDW01000017 Genomic DNA Translation: EXZ97344.1

Genome annotation databases

EnsemblBacteriaiEXZ91449; EXZ91449; M065_6033
EXZ92185; EXZ92185; M065_5451
EXZ92296; EXZ92296; M065_5312
EXZ96392; EXZ96392; M065_1263
EXZ96497; EXZ96497; M065_0917
EXZ96755; EXZ96755; M065_0708
EXZ96927; EXZ96927; M065_0352
EXZ97344; EXZ97344; M065_0245
PATRICifig|1339269.3.peg.1244

Similar proteinsi

Entry informationi

Entry nameiA0A016ENS4_BACFG
AccessioniPrimary (citable) accession number: A0A016ENS4
Entry historyiIntegrated into UniProtKB/TrEMBL: June 11, 2014
Last sequence update: June 11, 2014
Last modified: March 28, 2018
This is version 32 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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