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Overview

StatusReference proteome
Proteinsi16,652
Gene counti <p>This is the total number of unique genes found in the proteome set, algorithmically computed. For each gene, a single representative protein sequence is chosen from the proteome. Where possible, reviewed (Swiss-Prot) protein sequences are chosen as the representatives.</p> - Download one protein sequence per gene (FASTA)
Proteome IDi <p>The proteome identifier (UPID) is the unique identifier assigned to the set of proteins that constitute the <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a>. It consists of the characters ‘UP’ followed by 9 digits, is stable across releases and can therefore be used to cite a UniProt proteome.<p><a href='/help/proteome_id' target='_top'>More...</a></p>UP000008820
Taxonomy7159 - Aedes aegypti
StrainLiverpool/LVPib12
Last modifiedApril 21, 2018
Genome assembly and annotationi GCA_000004015.3 from ENA/EMBL

Aedes aegypti is the principal vector of the etiological agents of yellow fever, dengue fever and chikungunya fever. In 1901, Walter Reed and colleagues showed that yellow fever was transmitted by Aedes aegypti. Their work was based on Carlos Finlay's hypothesis that mosquito bites could transmit the organism causing the disease.

Due to its easy adaptation to laboratory culture it is the most studied species within the Culicinae, and has extensively contributed to our understanding of mosquito biology, physiology, genetics, and vector competence.

The Aedes aegypti complete genome sequence was published in 2007. It contains about 1.3 Gb, and approximately 16,000 protein-coding genes. About 47% of the genome consists of transposable elements, probably contributing to the expansion in size and organization of the Aedes aegypti genome.

Componentsi <p>Genomic components encoding the proteome</p>

Component nameGenome Accession(s)
Proteins
Unassembled WGS sequence16639
Mitochondrion13

Publications

  1. "The mitochondrial genome of the Yellow fever mosquito - Aedes aegypti."
    Lobo N.F., Lovin D., DeBruyn B., Puiu D., Shumway M., Haas B., Nene V., Severson D.W.
    Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases
  2. "Genome sequence of Aedes aegypti, a major arbovirus vector."
    Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J., Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F., Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P.
    Severson D.W.
    Science 2007:1718-1723(2007) [PubMed] [Europe PMC] [Abstract]
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