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StatusReference proteome
Proteinsi <p>Number of protein entries associated with this proteome: UniProtKB entries for regular proteomes or UniParc entries for redundant proteomes (<a href="/help/proteome_redundancy">more...</a>)</p> 5
Gene counti <p>This is the total number of unique genes found in the proteome set, algorithmically computed. For each gene, a single representative protein sequence is chosen from the proteome. Where possible, reviewed (Swiss-Prot) protein sequences are chosen as the representatives.</p> - Download one protein sequence per gene (FASTA)
Proteome IDi <p>The proteome identifier (UPID) is the unique identifier assigned to the set of proteins that constitute the <a href="">proteome</a>. It consists of the characters 'UP' followed by 9 digits, is stable across releases and can therefore be used to cite a UniProt proteome.<p><a href='/help/proteome_id' target='_top'>More...</a></p>UP000008479
Taxonomy10636 - Murine polyomavirus (strain A2)
Last modifiedMay 24, 2021
Genome assemblyi <p>Identifier for the genome assembly (<a href="">more...</a>)</p> from ENA/EMBL
Genome annotationi ENA/EMBL
Completenessi <p>Complete Proteome Detector (CPD) is an algorithm which employs statistical evaluation of the completeness and quality of proteomes in UniProt, by looking at the sizes of taxonomically close proteomes. Possible values are 'Standard', 'Close to Standard' and 'Outlier'.</p> Outlier (high value)

Componentsi <p>Genomic components encoding the proteome</p>

Component nameGenome Accession(s)
Component representationProteins


  1. "Multiple 5' terminal cap structures in late polyoma virus RNA."
    Flavell A.J., Cowie A., Legon S., Kamen R.
    Cell 16:357-371(1979) [PubMed] [Europe PMC] [Abstract]
  2. "Amplification in the leader sequence of late polyoma virus mRNAs."
    Legon S., Flavell A.J., Cowie A., Kamen R.
    Cell 16:373-388(1979) [PubMed] [Europe PMC] [Abstract]
  3. "DNA sequence alterations in Hr-t deletion mutants of polyoma virus."
    Hattori J., Carmichael G.G., Benjamin T.L.
    Cell 16:505-513(1979) [PubMed] [Europe PMC] [Abstract]
  4. "Sequence from early region of polyoma virus DNA containing viral replication origin and encoding small, middle and (part of) large T antigens."
    Soeda E., Arrand J.R., Smolar N., Griffin B.E.
    Cell 17:357-370(1979) [PubMed] [Europe PMC] [Abstract]
  5. "The nucleotide sequence and genome organization of the polyoma early region: extensive nucleotide and amino acid homology with SV40."
    Friedmann T., Esty A., LaPorte P., Deininger P.
    Cell 17:715-724(1979) [PubMed] [Europe PMC] [Abstract]
  6. "Nucleotide sequence and genetic organization of the polyoma late region: features common to the polyoma early region and SV40."
    Deininger P., Esty A., LaPorte P., Friedmann T.
    Cell 18:771-779(1979) [PubMed] [Europe PMC] [Abstract]
  7. "Expression of polyoma early functions in mouse embryonal carcinoma cells depends on sequence rearrangements in the beginning of the late region."
    Katinka M., Yaniv M., Vasseur M., Blangy D.
    Cell 20:393-399(1980) [PubMed] [Europe PMC] [Abstract]
  8. "Regulatory mutants of polyoma virus defective in DNA replication and the synthesis of early proteins."
    Bendig M.M., Thomas T., Folk W.R.
    Cell 20:401-409(1980) [PubMed] [Europe PMC] [Abstract]
  9. "Mutation near the polyoma DNA replication origin permits productive infection of F9 embryonal carcinoma cells."
    Fujimura F.K., Deininger P.L., Friedmann T., Linney E.
    Cell 23:809-814(1981) [PubMed] [Europe PMC] [Abstract]
  10. "Fine structure of the origin-proximal DNAase I-hypersensitive region in wild-type and EC mutant polyoma."
    Herbomel P., Saragosti S., Blangy D., Yaniv M.
    Cell 25:651-658(1981) [PubMed] [Europe PMC] [Abstract]
  11. "Organization of T antigens in the polyoma virus genome."
    Hunter T., Hutchinson M.A., Eckhart W., Friedmann T., Esty A., La Porte P., Deininger P.
    Cold Spring Harb. Symp. Quant. Biol. 44:131-139(1980) [PubMed] [Europe PMC] [Abstract]
  12. "The hr-t gene of polyoma virus."
    Benjamin T.L., Carmichael G.G., Schaffhausen B.S.
    Cold Spring Harb. Symp. Quant. Biol. 44:263-270(1980) [PubMed] [Europe PMC] [Abstract]
  13. "Early mutants of polyoma virus (dl8 and dl23) with altered transformation properties: is polyoma virus middle T antigen a transforming gene product?."
    Griffin B.E., Ito Y., Novak U., Spurr N., Dilworth S., Smolar N., Pollack R., Smith K., Rifkin D.B.
    Cold Spring Harb. Symp. Quant. Biol. 44:271-283(1980) [PubMed] [Europe PMC] [Abstract]
  14. "Comparison of polyoma virus transcription in productively infected mouse cells and transformed rodent cell lines."
    Kamen R., Favaloro J., Parker J., Treisman R., Lania L., Fried M., Mellor A.
    Cold Spring Harb. Symp. Quant. Biol. 44:63-75(1980) [PubMed] [Europe PMC] [Abstract]
  15. "Isolation and characterization of polyoma virus mutants which grow in murine embryonal carcinoma and trophoblast cells."
    Tanaka K., Chowdhury K., Chang K.S., Israel M., Ito Y.
    EMBO J. 1:1521-1527(1982) [PubMed] [Europe PMC] [Abstract]
  16. "T-antigen expression by polyoma mutants with modified RNA splicing."
    Nilsson S.V., Magnusson G.
    EMBO J. 2:2095-2101(1983) [PubMed] [Europe PMC] [Abstract]
  17. "Nucleotide sequence around the replication origin of polyoma virus DNA."
    Soeda E., Miura K., Nakaso A., Kimura G.
    FEBS Lett. 79:383-389(1977) [PubMed] [Europe PMC] [Abstract]
  18. "Nucleotide sequence studies of polyoma DNA. The Hpa II 3/5 junction to the Hpa II 4/Hae III 18 junction, encoding the origin of DNA replication and the 5' end of the early region."
    Friedmann T., LaPorte P., Esty A.
    J. Biol. Chem. 253:6561-6567(1978) [PubMed] [Europe PMC] [Abstract]
  19. "The structures of the spliced mRNAs encoding polyoma virus early region proteins."
    Treisman R., Cowie A., Favaloro J., Jat P., Kamen R.
    J. Mol. Appl. Genet. 1:83-92(1981) [PubMed] [Europe PMC] [Abstract]
  20. "5' termini of polyoma virus early region transcripts synthesized in vivo by wild-type virus and viable deletion mutants."
    Kamen R., Jat P., Treisman R., Favaloro J., Folk W.R.
    J. Mol. Biol. 159:189-224(1982) [PubMed] [Europe PMC] [Abstract]
  21. "Determination of sequences at the capped 5' ends of polyoma virus early region transcripts synthesized in vivo and in vitro demonstrates an unusual microheterogeneity."
    Cowie A., Jat P., Kamen R.
    J. Mol. Biol. 159:225-255(1982) [PubMed] [Europe PMC] [Abstract]
  22. "Non-contiguous segments of the polyoma genome required in cis for DNA replication."
    Luthman H., Nilsson M.G., Magnusson G.
    J. Mol. Biol. 161:533-550(1982) [PubMed] [Europe PMC] [Abstract]
  23. "Orientation of the complementary strands of polyoma virus DNA with respect to the DNA physical map."
    Kamen R., Sedat J., Ziff E.
    J. Virol. 17:212-218(1975) [PubMed] [Europe PMC] [Abstract]
  24. "Electron microscopic mapping of RNA transcribed from the late region of polyoma virus DNA."
    Manor H., Wu M., Baran N., Davidson N.
    J. Virol. 32:293-303(1979) [PubMed] [Europe PMC] [Abstract]
  25. "Isolation and characterization of polyoma virus genomes with deletions between the origin of viral DNA replication and the site of initiation of translation in the early region."
    Wells R.D., Hutchinson M.A., Eckhart W.
    J. Virol. 32:517-522(1979) [PubMed] [Europe PMC] [Abstract]
  26. "Deletion mutants of polyoma virus defining a nonessential region between the origin of replication and the initiation codon for early proteins."
    Bendig M.M., Folk W.R.
    J. Virol. 32:530-535(1979) [PubMed] [Europe PMC] [Abstract]
  27. "Viable deletion mutant in the medium and large T-antigen-coding sequences of the polyoma virus genome."
    Bendig M.M., Thomas T., Folk W.R.
    J. Virol. 33:1215-1220(1980) [PubMed] [Europe PMC] [Abstract]
  28. "Polyoma virus DNA: Sequence from the late region that specifies the leader sequence for late mRNA and codes for VP2, VP3, and the N-terminus of VP1."
    Arrand J.R., Soeda E., Walsh J.E., Smolar N., Griffin B.E.
    J. Virol. 33:606-618(1980) [PubMed] [Europe PMC] [Abstract]
  29. "Polyoma virus DNA: complete nucleotide sequence of the gene which codes for polyoma virus capsid protein VP1 and overlaps the VP2/VP3 genes."
    Soeda E., Arrand J.R., Griffin B.E.
    J. Virol. 33:619-630(1980) [PubMed] [Europe PMC] [Abstract]
  30. "Topography of the three late mRNA's of polyoma virus which encode the virion proteins."
    Kamen R., Favaloro J., Parker J.
    J. Virol. 33:637-651(1980) [PubMed] [Europe PMC] [Abstract]
  31. "Localization of three major cappe 5' ends of polyoma virus late mRNA's within a single tetranucleotide sequence in the viral genome."
    Flavell A.J., Cowie A., Arrand J.R., Kamen R.
    J. Virol. 33:902-908(1980) [PubMed] [Europe PMC] [Abstract]
  32. "Nucleotide sequence changes in polyoma virus A gene mutants."
    Thomas T., Vollmer P., Folk W.R.
    J. Virol. 37:1094-1098(1981) [PubMed] [Europe PMC] [Abstract]
  33. "Nucleotide sequence at polyoma VP1 mRNA splice sites."
    Srivatsan E.S., Deininger P.L., Friedmann T.
    J. Virol. 37:244-247(1981) [PubMed] [Europe PMC] [Abstract]
  34. "Nucleotide sequence changes in polyoma ts-a mutants: correlation with protein structure."
    Deininger P.L., LaPorte P., Friedmann T.
    J. Virol. 37:871-875(1981) [PubMed] [Europe PMC] [Abstract]
  35. "DNA sequences of polyoma virus early deletion mutants."
    Smolar N., Griffin B.E.
    J. Virol. 38:958-967(1981) [PubMed] [Europe PMC] [Abstract]
  36. "Characterization of polyoma mutants with altered middle and large T-antigens."
    Magnusson G., Nilsson M.G., Dilworth S.M., Smolar N.
    J. Virol. 39:673-683(1981) [PubMed] [Europe PMC] [Abstract]
  37. "Mutation causing premature termination of the polyoma virus medium T antigen blocks cell transformation."
    Templeton D., Eckhart W.
    J. Virol. 41:1014-1024(1982) [PubMed] [Europe PMC] [Abstract]
  38. "Polyoma virus mutant with normal transforming ability but impaired tumorigenic potential."
    Gelinas C., Chartrand P., Bastin M.
    J. Virol. 43:1072-1081(1982) [PubMed] [Europe PMC] [Abstract]
  39. "Physical and biological features of polyoma virus mutants able to infect embryonal carcinoma cell lines."
    Vasseur M., Katinka M., Herbomel P., Yaniv M., Blangy D.
    J. Virol. 43:800-808(1982) [PubMed] [Europe PMC] [Abstract]
  40. "mlt Mutants of polyoma virus."
    Ding D., Dilworth S.M., Griffin B.E.
    J. Virol. 44:1080-1083(1982) [PubMed] [Europe PMC] [Abstract]
  41. "Loss of polyoma virus infectivity as a result of a single amino acid change in a region of polyoma virus large T-antigen which has extensive amino acid homology with simian virus 40 large T-antigen."
    Hayday A.C., Chaudry F., Fried M.
    J. Virol. 45:693-699(1983) [PubMed] [Europe PMC] [Abstract]
  42. "Deletion mapping of a short polyoma virus middle T antigen segment important for transformation."
    Nilsson S.V., Tyndall C., Magnusson G.
    J. Virol. 46:284-287(1983) [PubMed] [Europe PMC] [Abstract]
  43. "DNA replication origin of polyoma virus: early proximal boundary."
    Katinka M., Yaniv M.
    J. Virol. 47:244-248(1983) [PubMed] [Europe PMC] [Abstract]
  44. "Polyomavirus origin for DNA replication comprises multiple genetic elements."
    Muller W.J., Mueller C.R., Mes A.M., Hassell J.A.
    J. Virol. 47:586-599(1983) [PubMed] [Europe PMC] [Abstract]
  45. "Polyomavirus large T antigen binds independently to multiple, unique regions on the viral genome."
    Pomerantz B.J., Mueller C.R., Hassell J.A.
    J. Virol. 47:600-610(1983) [PubMed] [Europe PMC] [Abstract]
  46. "Polyomavirus and simian virus 40 large T antigens bind to common DNA sequences."
    Pomerantz B.J., Hassell J.A.
    J. Virol. 49:925-937(1984) [PubMed] [Europe PMC] [Abstract]
  47. "Construction and functional characterization of polyomavirus genomes that separately encode the three early proteins."
    Zhu Z.Y., Veldman G.M., Cowie A., Carr A., Schaffhausen B., Kamen R.
    J. Virol. 51:170-180(1984) [PubMed] [Europe PMC] [Abstract]
  48. "mlt Mutation in the polyomavirus genome impairing a function of the middle T protein."
    Gelinas C., Masse S., Bastin M.
    J. Virol. 51:242-246(1984) [PubMed] [Europe PMC] [Abstract]
  49. "Essential nucleotides in the polyomavirus origin region."
    Triezenberg S.J., Folk W.R.
    J. Virol. 51:437-444(1984) [PubMed] [Europe PMC] [Abstract]
  50. "Multiple binding sites for polyomavirus large T antigen within regulatory sequences of polyomavirus DNA."
    Cowie A., Kamen R.
    J. Virol. 52:750-760(1984) [PubMed] [Europe PMC] [Abstract]
  51. "Isolation of polyomavirus mutants multiadapted to murine embryonal carcinoma cells."
    Melin F., Pinon H., Kress C., Blangy D.
    J. Virol. 53:862-866(1985) [PubMed] [Europe PMC] [Abstract]
  52. "Simian virus 40 and polyomavirus large tumor antigens have different requirements for high-affinity sequence-specific DNA binding."
    Scheller A., Prives C.
    J. Virol. 54:532-545(1985) [PubMed] [Europe PMC] [Abstract]
  53. "Deletions of N-terminal sequences of polyoma virus T-antigens reduce but do not abolish transformation of rat fibroblasts."
    Katinka M., Yaniv M.
    Mol. Cell. Biol. 2:1238-1246(1982) [PubMed] [Europe PMC] [Abstract]
  54. "DNA sequences required for specific and efficient initiation of transcription at the polyoma virus early promoter."
    Jat P., Novak U., Cowie A., Tyndall C., Kamen R.
    Mol. Cell. Biol. 2:737-751(1982) [PubMed] [Europe PMC] [Abstract]
  55. "N-terminal amino acid sequences of the polyoma middle-size T antigen are important for protein kinase activity and cell transformation."
    Templeton D., Eckhart W.
    Mol. Cell. Biol. 4:817-821(1984) [PubMed] [Europe PMC] [Abstract]
  56. "Polyomavirus mutation that confers a cell-specific cis advantage for viral DNA replication."
    De Simone V., La Mantia G., Lania L., Amati P.
    Mol. Cell. Biol. 5:2142-2146(1985) [PubMed] [Europe PMC] [Abstract]
  57. "Polyomavirus enhancer contains multiple redundant sequence elements that activate both DNA replication and gene expression."
    Veldman G.M., Lupton S., Kamen R.
    Mol. Cell. Biol. 5:649-658(1985) [PubMed] [Europe PMC] [Abstract]
  58. "Amino acid sequence homology between polyoma and SV40 tumour antigens deduced from nucleotide sequences."
    Friedmann T., Doolittle R.F., Walter G.
    Nature 274:291-293(1978) [PubMed] [Europe PMC] [Abstract]
  59. "Sequences from the genome of a non-transforming mutant of polyoma virus."
    Soeda E., Griffin B.E.
    Nature 276:294-298(1978) [PubMed] [Europe PMC] [Abstract]
  60. "Coding potential and regulatory signals of the polyoma virus genome."
    Soeda E., Arrand J.R., Smolar N., Walsh J.E., Griffin B.E.
    Nature 283:445-453(1980) [PubMed] [Europe PMC] [Abstract]
  61. "Polyoma DNA sequences involved in control of viral gene expression in murine embryonal carcinoma cells."
    Katinka M., Vasseur M., Montreau N., Yaniv M., Blangy D.
    Nature 290:720-722(1981) [PubMed] [Europe PMC] [Abstract]
  62. "Transformation of rat cells by an altered polyoma virus genome expressing only the middle-T protein."
    Treisman R., Novak U., Favaloro J., Kamen R.
    Nature 292:595-600(1981) [PubMed] [Europe PMC] [Abstract]
  63. "Transforming activity of polyoma virus middle-T antigen probed by site-directed mutagenesis."
    Oostra B.A., Harvey R., Ely B.K., Markham A.F., Smith A.E.
    Nature 304:456-459(1983) [PubMed] [Europe PMC] [Abstract]
  64. "Comparison of the polyoma virus early and late promoters by transcription in vitro."
    Jat P., Roberts J.W., Cowie A., Kamen R.
    Nucleic Acids Res. 10:871-887(1982) [PubMed] [Europe PMC] [Abstract]
  65. "Polyoma infected cells contain at least three spliced late RNAs."
    Horowitz M., Bratosin S., Aloni Y.
    Nucleic Acids Res. 5:4663-4675(1978) [PubMed] [Europe PMC] [Abstract]
  66. "Polyoma virus. The early region and its T-antigens."
    Soeda E., Arrand J.R., Griffin B.E.
    Nucleic Acids Res. 7:839-857(1979) [PubMed] [Europe PMC] [Abstract]
  67. "Characterisation of polyoma late mRNA leader sequences by molecular cloning and DNA sequence analysis."
    Treisman R.
    Nucleic Acids Res. 8:4867-4888(1980) [PubMed] [Europe PMC] [Abstract]
  68. "The nucleotide sequence and restriction enzyme sites of the polyoma genome."
    Deninger P.L., Esty A., LaPorte P., Hsu H., Friedmann T.
    Nucleic Acids Res. 8:855-860(1980) [PubMed] [Europe PMC] [Abstract]
  69. "Requirement for the C-terminal region of middle T-antigen in cellular transformation by polyoma virus."
    Novak U., Griffin B.E.
    Nucleic Acids Res. 9:2055-2073(1981) [PubMed] [Europe PMC] [Abstract]
  70. "The high affinity binding site on polyoma virus DNA for the viral large-T protein."
    Gaudray P., Tyndall C., Kamen R., Cuzin F.
    Nucleic Acids Res. 9:5697-5710(1981) [PubMed] [Europe PMC] [Abstract]
  71. "A region of the polyoma virus genome between the replication origin and late protein coding sequences is required in cis for both early gene expression and viral DNA replication."
    Tyndall C., La Mantia G., Thacker C.M., Favaloro J., Kamen R.
    Nucleic Acids Res. 9:6231-6250(1981) [PubMed] [Europe PMC] [Abstract]
  72. "Sequences at the capped 5'-ends of polyoma virus late region mRNAs: an example of extreme terminal heterogeneity."
    Cowie A., Tyndall C., Kamen R.
    Nucleic Acids Res. 9:6305-6322(1981) [PubMed] [Europe PMC] [Abstract]
  73. "Similarity of nucleotide sequences around the origin of DNA replication in mouse polyoma virus and simian virus 40."
    Soeda E., Kimura G., Miura K.
    Proc. Natl. Acad. Sci. U.S.A. 75:162-166(1978) [PubMed] [Europe PMC] [Abstract]
  74. "Isolation and characterization of polyoma host range mutants that replicate in nullipotential embryonal carcinoma cells."
    Sekikawa K., Levine A.J.
    Proc. Natl. Acad. Sci. U.S.A. 78:1100-1104(1981) [PubMed] [Europe PMC] [Abstract]
  75. "A mutation increasing the size of the polyoma virion proteins, VP2 and VP3."
    Eckhart W., Delbruck S., Deininger P., Friedmann T., Hunter T.
    Virology 109:35-46(1981) [PubMed] [Europe PMC] [Abstract]
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