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Overview

Proteinsi3,661
Gene counti - Download one protein sequence per gene (FASTA)
Proteome IDiUP000008319
Taxonomy529507 - Proteus mirabilis (strain HI4320)
StrainHI4320
Last modifiedMay 25, 2018
Genome assembly and annotationi GCA_000069965.1 from ENA/EMBL
Pan proteomei This proteome is part of the Cosenzaea myxofaciens ATCC 19692 pan proteome (fasta)

The gram-negative enteric bacterium Proteus mirabilis, a human commensal bacterium, is a frequent cause of urinary tract infections in individuals with long-term indwelling catheters or with complicated urinary tracts (e.g., due to spinal cord injury or anatomic abnormality). Infection may lead to acute pyelonephritis, fever, bacteremia, the formation of kidney and bladder stones or the encrustation or obstruction of indwelling urinary catheters. It is highly motile and differentiates from short vegetative swimmer cells to an elongated, highly flagellated swarmer form. It has strong adherence abilities, which enable it to infect the bladder, kidney and even penetrate into the bloodstream.

Strain HI4320 was isolated from the urine of a nursing home patient with a long-term (>30 days) indwelling urinary catheter. It is not only able to degrade urine but analysis of the genome suggests it may also be able to synthesize it. The genome encodes 17 types of fimbriae, more than in any other bacterium sequenced to date, highlighting the importance of adherence to this organism. This strain is considered a low-passage clinical isolate (adapted from PubMed 18375554).

Componentsi

Component nameGenome Accession(s)
Proteins
Chromosome3606
Plasmid pHI432055
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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