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StatusReference proteome
Proteinsi <p>Number of protein entries associated with this proteome: UniProtKB entries for regular proteomes or UniParc entries for redundant proteomes (<a href="/help/proteome%5Fredundancy">more...</a>)</p> 939
Gene counti <p>This is the total number of unique genes found in the proteome set, algorithmically computed. For each gene, a single representative protein sequence is chosen from the proteome. Where possible, reviewed (Swiss-Prot) protein sequences are chosen as the representatives.</p> - Download one protein sequence per gene (FASTA)
Proteome IDi <p>The proteome identifier (UPID) is the unique identifier assigned to the set of proteins that constitute the <a href="">proteome</a>. It consists of the characters 'UP' followed by 9 digits, is stable across releases and can therefore be used to cite a UniProt proteome.<p><a href='/help/proteome_id' target='_top'>More...</a></p>UP000007307
Taxonomy320483 - Anaplasma marginale (strain Florida)
Last modifiedJanuary 15, 2020
Genome assembly and annotationi <p>Identifier for the genome assembly (<a href="">more...</a>)</p> GCA_000020305.1 from ENA/EMBL full
Pan proteomei <p>A pan proteome is the full set of proteins thought to be expressed by a group of highly related organisms (e.g. multiple strains of the same bacterial species).<p><a href='/help/pan_proteomes' target='_top'>More...</a></p> This proteome is part of the Anaplasma marginale (strain Florida) pan proteome (fasta)

Anaplasma marginale is the most prevalent tick-borne pathogen of cattle. It is transmitted by ixodid ticks. Symptoms of acute disease are anemia, weight loss, and often death. A.marginale establishes life-long persistent infection in animals that survive disease. These animals are clinically healthy but serve as reservoirs for transmission of the pathogen. Sequencing has revealed a small genome size due to reductive evolution, and it is related to several other intracellular pathogens, including those in the genera Ehrlichia, and Rickettsia. The Florida strain was originally isolated from a pool of blood samples collected from cattle in 1955. It is not able to be transmitted by the tick Dermacentor andersoni. It has been passed continuously since isolation. Comparisons between 2 fully sequenced genomes (strains St. Maries and Florida) and 3 unfinished genomes (two tick transmissible strains; Virginia and Puerto Rico, and one D.andersoni non-transmissible strain, Mississippi) showed that A. marginale has a closed-core genome with few highly plastic regions, which include the msp2 and msp3 genes, as well as the aaap locus. This means that few to no new genes are expected to be found when new genomes are sequenced. It has however a medium level of single-nucleotide polymorphisms (SNPs), having at least 20,028 variable sites found among these five genomes which is approximately 1.67% of the estimated size of the pan-genome.

Componentsi <p>Genomic components encoding the proteome</p>

Component nameGenome Accession(s)
Component representationProteins


  1. "Conservation in the face of diversity: multistrain analysis of an intracellular bacterium."
    Dark M.J., Herndon D.R., Kappmeyer L.S., Gonzales M.P., Nordeen E., Palmer G.H., Knowles D.P. Jr., Brayton K.A.
    BMC Genomics 10:16-16(2009) [PubMed] [Europe PMC] [Abstract]
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