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Overview

StatusReference proteome
Proteinsi <p>Number of protein entries associated with this proteome: UniProtKB entries for regular proteomes or UniParc entries for redundant proteomes (<a href="/help/proteome%5Fredundancy">more...</a>)</p> 17,089
Gene counti <p>This is the total number of unique genes found in the proteome set, algorithmically computed. For each gene, a single representative protein sequence is chosen from the proteome. Where possible, reviewed (Swiss-Prot) protein sequences are chosen as the representatives.</p> - Download one protein sequence per gene (FASTA)
Proteome IDi <p>The proteome identifier (UPID) is the unique identifier assigned to the set of proteins that constitute the <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a>. It consists of the characters 'UP' followed by 9 digits, is stable across releases and can therefore be used to cite a UniProt proteome.<p><a href='/help/proteome_id' target='_top'>More...</a></p>UP000007062
Taxonomy7165 - Anopheles gambiae
StrainPEST
Last modifiedJanuary 29, 2021
Genome assembly and annotationi <p>Identifier for the genome assembly (<a href="https://www.ensembl.org/Help/Faq?id=216">more...</a>)</p> GCA_000005575.1 from EnsemblMetazoa full
Buscoi <p>The Benchmarking Universal Single-Copy Ortholog (BUSCO) assessment tool is used, for eukaryotic and bacterial proteomes, to provide quantitative measures of UniProt proteome data completeness in terms of expected gene content. BUSCO scores include percentages of complete (C) single-copy (S) genes, complete (C) duplicated (D) genes, fragmented (F) and missing (F) genes, as well as the total number of orthologous clusters (n) used in the BUSCO assessment.</p> C:98.1%[S:21.5%,D:76.6%],F:0.5%,M:1.4%,n:3285 diptera_odb10
Completenessi <p>Complete Proteome Detector (CPD) is an algorithm which employs statistical evaluation of the completeness and quality of proteomes in UniProt, by looking at the sizes of taxonomically close proteomes. Possible values are 'Standard', 'Close to Standard' and 'Outlier'.</p> Close to standard (high)

Anopheles gambiae is the primary mosquito vector responsible for the transmission of malaria (Plasmodium falciparum) in most of sub-Saharan Africa; and is also considered to be one of the most efficient vectors of malaria. It feeds almost exclusively on humans, late at night, indoors as well as outdoors. Anopholes gambiae can show more opportunistic feeding behaviors depending on location, host availability and the genetic make-up of the mosquito population. The larvae develop in temporary bodies of fresh water and the adults rest primarily indoors, but resting outdoors has also been observed.

The Anopheles gambiae complete genome sequence of the strain PEST was published in 2002. It contains about 280 Mb, and approximately 12,800 protein-coding genes. The high degree of genetic variation observed in the strain PEST is probably the result of recombination among the different cytotypes that contributed to the PEST strain, resulting in a mosaic genome.

Componentsi <p>Genomic components encoding the proteome</p>

Component nameGenome Accession(s)
Component representationProteins
Chromosome 2L3741
Chromosome 2R4597
Chromosome 3L3058
Chromosome 3R3765
Chromosome X1416
Mitochondrion13
Unassembled WGS sequence504
Unplaced
1

Publications

  1. "The mitochondrial genome of the mosquito Anopheles gambiae: DNA sequence, genome organization, and comparisons with mitochondrial sequences of other insects."
    Beard C.B., Hamm D.M., Collins F.H.
    Insect Mol. Biol. 2:103-124(1993) [PubMed] [Europe PMC] [Abstract]
  2. "The genome sequence of the malaria mosquito Anopheles gambiae."
    Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R., Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R., Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z., Kraft C.L., Abril J.F.
    Hoffman S.L.
    Science 298:129-149(2002) [PubMed] [Europe PMC] [Abstract]
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