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StatusReference proteome
Proteinsi <p>Number of protein entries associated with this proteome: UniProtKB entries for regular proteomes or UniParc entries for redundant proteomes (<a href="/help/proteome%5Fredundancy">more...</a>)</p> 9,551
Gene counti <p>This is the total number of unique genes found in the proteome set, algorithmically computed. For each gene, a single representative protein sequence is chosen from the proteome. Where possible, reviewed (Swiss-Prot) protein sequences are chosen as the representatives.</p> - Download one protein sequence per gene (FASTA)
Proteome IDi <p>The proteome identifier (UPID) is the unique identifier assigned to the set of proteins that constitute the <a href="">proteome</a>. It consists of the characters 'UP' followed by 9 digits, is stable across releases and can therefore be used to cite a UniProt proteome.<p><a href='/help/proteome_id' target='_top'>More...</a></p>UP000006138
Taxonomy713604 - Amycolatopsis mediterranei (strain S699)
Last modifiedJanuary 15, 2020
Genome assembly and annotationi <p>Identifier for the genome assembly (<a href="">more...</a>)</p> GCA_000220945.1 from ENA/EMBL full
Pan proteomei <p>A pan proteome is the full set of proteins thought to be expressed by a group of highly related organisms (e.g. multiple strains of the same bacterial species).<p><a href='/help/pan_proteomes' target='_top'>More...</a></p> This proteome is part of the Amycolatopsis mediterranei (strain S699) (Nocardia mediterranei) pan proteome (fasta)
CompletenessClose to Standard

Amycolatopsis mediterranei is a soil bacterium which produces rifamycin B, an antibiotic used against various Mycobacterium infections. Strain S699 is a derivative of the original type strain (ATCC 13685) isolated in 1957 from a soil sample from a pine arboretum in France. It was first named Streptomyces mediterranei, later Nocardia mediterranea, and finally Amycolatopsis mediterranei.

A.mediterranei forms branching vegetative hyphae with a diameter of 0.5 to 2.0um, which tend to zig-zag. Spores, when formed, are found on the aerial hyphae and are ellipsoid to oblong, straight to flexous chains. Grows from 10 to 42 degrees Celsius, is non-acidfast, non-motile, aerobic and catalase-positive (adapted from 1986, Lechevalier et al., Int. J. Syst. Bacteriol. 36:29-37).

As of September 2013, 2 different groups have sequenced S699 using different techniques and assembly processes. The other S699 genome (CP003729) has 218 single nucleotide polymorphisms (SNPs) and 51 insertion/deletions compared to this one (CP002896), which the authors of the other study attribute to different assembly strategies (adapted from PMIDs 21914879 and 23012281).

Componentsi <p>Genomic components encoding the proteome</p>

Component nameGenome Accession(s)
Component representationProteins


  1. "Whole genome sequence of the rifamycin B-producing strain Amycolatopsis mediterranei S699."
    Verma M., Kaur J., Kumar M., Kumari K., Saxena A., Anand S., Nigam A., Ravi V., Raghuvanshi S., Khurana P., Tyagi A.K., Khurana J.P., Lal R.
    J. Bacteriol. 193:5562-5563(2011) [PubMed] [Europe PMC] [Abstract]
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