Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.


StatusReference proteome
Proteome IDiUP000005440
Taxonomy134676 - Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110)
StrainATCC 31044 / CBS 674.73 / SE50/110
Last modifiedFebruary 27, 2018
Genome assembly and annotationi GCA_000237145.1 from ENA/EMBL

Actinoplanes sp. SE50/110 is an actinomycete originally isolated near Ruiru, Kenya in 1969. Derivatives of this strain are used in the industrial produciton of the alpha-glucosidase inhibitor acarbose, (O-[4,6-dideoxy-4[1 s-(1,4,6/5)-4,5,6-trihydroxy-3-hydroxymethyl-2-cyclohexen-1-yl]-amino-alpha-D-glucopyranosyl]-(1-->4)- O-alpha-D-glucopyranosyl-(1-->4)-D-glucopyranose). Acarbose has been used since 1990 in the therapy of diabetes type II, in order to enable patients to better control blood sugar contents while living with starch-containing diets. With a mean G+C content of 71.32% the genome is difficult to sequence, but after considerable effort it has been determined to consist of 9,239,851 bp (adapted from PMIDs 21536083, 14669056 and


DownloadView all proteins
Component nameGenome Accession(s)


  1. "The complete genome sequence of the acarbose producer Actinoplanes sp. SE50/110."
    Schwientek P., Szczepanowski R., Kalinowski J., Klein A., Selber K., Wehmeier U.F., Stoye J., Puehler A.
    Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health