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Overview

StatusReference proteome
Proteins3,258
Proteome IDiUP000002676
Taxonomy257313 - Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)
StrainTohama I / ATCC BAA-589 / NCTC 13251
Last modifiedFebruary 27, 2018
Genome assembly and annotationi GCA_000195715.1 from ENA/EMBL
Pan proteomei This proteome is part of the Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251) pan proteome (fasta)

The genus Bordetella contains nine designated species, three of which are so closely related that they are considered subspecies and are referred to as the "classical Bordetella"; B. pertussis, B. parapertussis and B. bronchiseptica. Although highly similar at the DNA sequence level, these 3 vary in host specificity, severity of diseases, and their ability to cause acute versus chronic infection. B. bronchiseptica causes infections ranging from lethal pneumonia to asymptomatic respiratory carriage and chronically colonizes the respiratory tracts of various mammalian hosts, with some lineages primarily isolated from humans. B. pertussis and B. parapertussis(hu), which are thought to have evolved independently from a B. bronchiseptica-like progenitor, are causative agents of whooping cough in humans. Another distinct lineage only isolated from sheep has been designated B. parapertussis(ov). Comparison of seven divergent classical Bordetella isolates shows only approximately 50% of genes are shared by all strains in the core genome consisting of 2,857 gene families. The pan-genome consists of at least 5,558 gene families; analysis suggests that the classical Bordetellae pan-genome is "open" with limited gene acquisition, although some evidence of horizontal gene transfer is seen.

Bordetella pertussis is a human pathogen which colonizes the respiratory tract. It is the etiologic agent of whooping cough.

Componentsi

DownloadView all proteins
Component nameGenome Accession(s)
Proteins
Chromosome3258

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