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Overview

StatusReference proteome
Proteinsi29,952
Gene counti <p>This is the total number of unique genes found in the proteome set, algorithmically computed. For each gene, a single representative protein sequence is chosen from the proteome. Where possible, reviewed (Swiss-Prot) protein sequences are chosen as the representatives.</p> - Download one protein sequence per gene (FASTA)
Proteome IDi <p>The proteome identifier (UPID) is the unique identifier assigned to the set of proteins that constitute the <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a>. It consists of the characters ‘UP’ followed by 9 digits, is stable across releases and can therefore be used to cite a UniProt proteome.<p><a href='/help/proteome_id' target='_top'>More...</a></p>UP000002494
Taxonomy10116 - Rattus norvegicus
StrainBrown Norway
Last modifiedOctober 22, 2018
Genome assembly and annotationi GCA_000001895.4 from Ensembl

Rattus norvegicus (also called the brown rat, Hanover rat, Norwegian rat, Brown Norway rat) is a common rodent closely related to mouse. The species originated in Asia, not Norway as the name suggests, and has spread throughout the world.

The rat is a major pest and a reservoir of pathogens, being involved in the transmission of infectious diseases such as cholera, bubonic plague and typhus. On the other hand, Rattus norvegicus was the first mammalian species to be domesticated for scientific research.

The rat is an indispensable model organism in biomedical research, especially in cardiovascular and psychological research, and in therapeutic efficacy and toxicity studies. It is the third mammalian species to have its genome sequenced.

The reference proteome of Rattus norvegicus is derived from the genome sequence of strain Brown Norway (BN) that was published in 2004. The sequence data were mostly from two inbred female animals of strain BN/SsNHsd/Mcwi. The assembled genome size is 2.75 Gb.

Componentsi <p>Genomic components encoding the proteome</p>

Component nameGenome Accession(s)
Proteins
Unplaced
3120
Mitochondrion13
Chromosome 13557
Chromosome 21760
Chromosome 32116
Chromosome 41644
Chromosome 51598
Chromosome 61134
Chromosome 71629
Chromosome 81481
Chromosome 91071
Chromosome 102096
Chromosome 11716
Chromosome 12820
Chromosome 13839
Chromosome 14844
Chromosome 15855
Chromosome 16769
Chromosome 17756
Chromosome 18638
Chromosome 19667
Chromosome 20861
Chromosome X1017
Chromosome Y12

Publications

  1. "The Mitochondrial Genome of Rattus Norvegicus strain Brown Norway."
    McLeod M.P., Muzny D.M., Metzker M.L., Abramzon S., Adams C., Alder J., Allen C., Allen H., Alsbrooks S., Amin A., Anguiano D., Anyalebechi V., Aoyagi A., Ayodeji M., Baca E., Baden H., Baldwin D., Bandaranaike D.
    Gibbs R.A.
    Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases
  2. Submitted (NOV-2002) to the EMBL/GenBank/DDBJ databases
  3. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    Collins F.S.
    Nature 2004:493-521(2004) [PubMed] [Europe PMC] [Abstract]
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