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Overview

StatusReference proteome
Proteins29,961
Proteome IDiUP000002494
Taxonomy10116 - Rattus norvegicus
StrainBrown Norway
Last modifiedMay 26, 2018
Genome assembly and annotationi GCA_000001895.4 from Ensembl
© www.nenature.com

Rattus norvegicus (also called the brown rat, Hanover rat, Norwegian rat, Brown Norway rat) is a common rodent closely related to mouse. The species originated in Asia, not Norway as the name suggests, and has spread throughout the world.

The rat is a major pest and a reservoir of pathogens, being involved in the transmission of infectious diseases such as cholera, bubonic plague and typhus. On the other hand, Rattus norvegicus was the first mammalian species to be domesticated for scientific research.

The rat is an indispensable model organism in biomedical research, especially in cardiovascular and psychological research, and in therapeutic efficacy and toxicity studies. It is the third mammalian species to have its genome sequenced.

The reference proteome of Rattus norvegicus is derived from the genome sequence of strain Brown Norway (BN) that was published in 2004. The sequence data were mostly from two inbred female animals of strain BN/SsNHsd/Mcwi. The assembled genome size is 2.75 Gb.

Componentsi

DownloadView all proteins
Component nameGenome Accession(s)
Proteins
Unplaced
3121
Mitochondrion13
Chromosome 13558
Chromosome 21758
Chromosome 32115
Chromosome 41645
Chromosome 51599
Chromosome 61135
Chromosome 71628
Chromosome 81481
Chromosome 91072
Chromosome 102096
Chromosome 11717
Chromosome 12820
Chromosome 13838
Chromosome 14846
Chromosome 15855
Chromosome 16768
Chromosome 17757
Chromosome 18638
Chromosome 19667
Chromosome 20863
Chromosome X1019
Chromosome Y12

Publications

  1. "The Mitochondrial Genome of Rattus Norvegicus strain Brown Norway."
    McLeod M.P., Muzny D.M., Metzker M.L., Abramzon S., Adams C., Alder J., Allen C., Allen H., Alsbrooks S., Amin A., Anguiano D., Anyalebechi V., Aoyagi A., Ayodeji M., Baca E., Baden H., Baldwin D., Bandaranaike D.
    , Barber M., Barnstead M., Benahmed F., Biswalo K., Blair J., Blankenburg K., Blyth P., Brown M., Bryant N., Buhay C., Burch P., Burrell K., Calderon E., Cardenas V., Carter K., Cavazos I., Ceasar H., Center A., Chacko J., Chavez D., Chen G., Chen R., Chen Y., Chen Z., Chu J., Cleveland C., Cockrell R., Cox C., Coyle M., Cree A., D'Souza L., Davila M.L., Davis C., Davy-Carroll L., De Anda C., Dederich D., Delgado O., Denson S., Deramo C., Ding Y., Dinh H., Divya K., Draper H., Dugan-Rocha S., Dunn A., Durbin K., Duval B., Eaves K., Egan A., Escotto M., Eugene C., Evans C.A., Falls T., Fan G., Fernandez S., Finley M., Flagg N., Forbes L., Foster M., Foster P., Fraser C.M., Gabisi A., Ganta R., Garcia A., Garner T., Garza M., Gebregeorgis E., Geer K., Gill R., Grady M., Guerra W., Guevara W., Gunaratne P., Haaland W., Hamil C., Hamilton C., Hamilton K., Harvey Y., Havlak P., Hawes A., Henderson N., Hernandez J., Hernandez R., Hines S., Hladun S.L., Hodgson A., Hogues M., Hollins B., Howells S., Hulyk S., Hume J., Idlebird D., Jackson A., Jackson L., Jacob L., Jiang H., Johnson B., Johnson R., Jolivet A., Karpathy S., Kelly S., Kelly S., Khan Z., King L., Kovar C., Kowis C., Kraft C.L., Lebow H., Levan J., Lewis L., Li Z., Liu J., Liu J., Liu W., Liu Y., London P., Longacre S., Lopez J., Lorensuhewa L., Loulseged H., Lozado R.J., Lu X., Ma J., Maheshwari M., Mahindartne M., Mahmoud M., Malloy K., Mangum A., Mangum B., Mapua P., Martin K., Martin R., Martinez E., Mawhiney S., McNeill T.Z., Meenen E., Milosavljevic A., Miner G., Minja E., Montemayor J., Moore S., Morgan M., Morris K., Morris S., Munidasa M., Murphy M., Nair L., Nankervis C., Neal D., Newton N., Nguyen N., Norris S., Nwaokelemeh O., Okwuonu G., Olarnpunsagoon A., Pal S., Parks K., Pasternak S., Paul H., Perez A., Perez L., Pfannkoch C., Plopper F., Poindexter A., Popovic D., Primus E., Pu L.-L., Puazo M., Quiroz J., Rachlin E., Reeves K., Regier M.A., Reigh R., Reilly B., Reilly M., Ren Y., Reuter M., Richards S., Riggs F., Rives C., Rodkey T., Rojas A., Rose M., Rose R., Ruiz S.J., Sanders W., Savery G., Scherer S., Scott G., Shatsman S., Shen H., Shetty J., Shvartsbeyn A., Sisson I., Sitter C.D., Smajs D., Sneed A., Sodergren E., Song X.-Z., Sorelle R., Sosa J., Steimle M., Strong R., Sutton A., Svatek A., Tabor P., Taylor C., Taylor T., Thomas N., Thomas S., Tingey A., Trejos Z., Usmani K., Valas R., Vera V., Villasana D., Waldron L., Walker B., Wang J., Wang Q., Wang S., Warren J., Warren R., Wei X., White F., Williams G., Willson R., Wleczyk R., Wooden H., Worley K., Wright D., Wright R., Wu J., Yakub S., Yen J., Yoon L., Yoon V., Yu F., Zhang J., Zhou J., Zhou X., Zhao S., Dunn D., von Niederhausern A., Weiss R., Smith D.R., Holt R.A., Smith H.O., Weinstock G., Gibbs R.A.
    Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases
  2. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 2004:493-521(2004) [PubMed] [Europe PMC] [Abstract]
  3. Submitted (NOV-2002) to the EMBL/GenBank/DDBJ databases

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