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StatusReference proteome
Proteinsi <p>Number of protein entries associated with this proteome: UniProtKB entries for regular proteomes or UniParc entries for redundant proteomes (<a href="/help/proteome%5Fredundancy">more...</a>)</p> 6,364
Gene counti <p>This is the total number of unique genes found in the proteome set, algorithmically computed. For each gene, a single representative protein sequence is chosen from the proteome. Where possible, reviewed (Swiss-Prot) protein sequences are chosen as the representatives.</p> - Download one protein sequence per gene (FASTA)
Proteome IDi <p>The proteome identifier (UPID) is the unique identifier assigned to the set of proteins that constitute the <a href="">proteome</a>. It consists of the characters 'UP' followed by 9 digits, is stable across releases and can therefore be used to cite a UniProt proteome.<p><a href='/help/proteome_id' target='_top'>More...</a></p>UP000002429
Taxonomy266264 - Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34)
StrainATCC 43123 / DSM 2839 / NBRC 102507 / CH34
Last modifiedMay 4, 2020
Genome assembly and annotationi <p>Identifier for the genome assembly (<a href="">more...</a>)</p> GCA_000196015.1 from ENA/EMBL full
Pan proteomei <p>A pan proteome is the full set of proteins thought to be expressed by a group of highly related organisms (e.g. multiple strains of the same bacterial species).<p><a href='/help/pan_proteomes' target='_top'>More...</a></p> This proteome is part of the Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34) (Ralstonia metallidurans) pan proteome (fasta)
CompletenessClose to Standard

Ralstonia metallidurans CH34, formerly known as Ralstonia eutropha and Alcaligenes eutrophus, is a gram-negative, non-spore forming bacillus that flourishes in millimolar concentrations of toxic heavy metals. Its optimal growth temperature is 30 degrees C. Although the type strain, CH34, was first isolated in 1976 from the sludge of a zinc decantation tank in Belgium that was polluted with high concentrations of several heavy metals, it and other metal-resistant members of the genus Ralstonia are frequently found in sediments and soils with a high content of heavy metals from diverse geographical locations. A typical feature of these metal-resistant Ralstonia is the presence of one or two large megaplasmids which contain genes for multiple resistances to heavy metals. The reference strain, CH34, which was selected for its capacity to grow on minimal salt medium of low complexity containing cobalt, zinc, and cadmium ions, contains two large plasmids, pMOL28 (180 kb) and pMOL30 (240 kb). Together these plasmids confer resistance to Zn, Cd, Co, Pb, Cu, Hg , Ni and Cr. Both plasmids are low copy number and stably maintained even without selective pressure. They are self-transferable at low frequencies. The Minimal Inhibitory Concentration (MIC) for free, non-chelated Ni, Co, Zn and Cd are 2.5, 20, 12 and 2.5 mM, respectively for the reference strain. There is also a megaplasmid of about 2600 kb.

Componentsi <p>Genomic components encoding the proteome</p>

Component nameGenome Accession(s)
Component representationProteins
Plasmid megaplasmid CH342362
Plasmid pMOL30192
Plasmid pMOL28151


  1. "The complete genome sequence of Cupriavidus metallidurans strain CH34, a master survivalist in harsh and anthropogenic environments."
    Janssen P.J., Van Houdt R., Moors H., Monsieurs P., Morin N., Michaux A., Benotmane M.A., Leys N., Vallaeys T., Lapidus A., Monchy S., Medigue C., Taghavi S., McCorkle S., Dunn J., van der Lelie D., Mergeay M.
    PLoS ONE 5:E10433-E10433(2010) [PubMed] [Europe PMC] [Abstract]
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