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Overview

StatusReference proteome
Proteinsi <p>Number of protein entries associated with this proteome: UniProtKB entries for regular proteomes or UniParc entries for redundant proteomes (<a href="/help/proteome%5Fredundancy">more...</a>)</p> 45,351
Gene counti <p>This is the total number of unique genes found in the proteome set, algorithmically computed. For each gene, a single representative protein sequence is chosen from the proteome. Where possible, reviewed (Swiss-Prot) protein sequences are chosen as the representatives.</p> - Download one protein sequence per gene (FASTA)
Proteome IDi <p>The proteome identifier (UPID) is the unique identifier assigned to the set of proteins that constitute the <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a>. It consists of the characters 'UP' followed by 9 digits, is stable across releases and can therefore be used to cite a UniProt proteome.<p><a href='/help/proteome_id' target='_top'>More...</a></p>UP000002254
Taxonomy9615 - Canis lupus familiaris
StrainBoxer
Last modifiedDecember 21, 2020
Genome assembly and annotationi <p>Identifier for the genome assembly (<a href="https://www.ensembl.org/Help/Faq?id=216">more...</a>)</p> GCA_000002285.2 from Ensembl full
Buscoi <p>The Benchmarking Universal Single-Copy Ortholog (BUSCO) assessment tool is used, for eukaryotic and bacterial proteomes, to provide quantitative measures of UniProt proteome data completeness in terms of expected gene content. BUSCO scores include percentages of complete (C) single-copy (S) genes, complete (C) duplicated (D) genes, fragmented (F) and missing (F) genes, as well as the total number of orthologous clusters (n) used in the BUSCO assessment.</p> C:92.2%[S:76.8%,D:15.4%],F:1.5%,M:6.3%,n:14502 carnivora_odb10
Completenessi <p>Complete Proteome Detector (CPD) is an algorithm which employs statistical evaluation of the completeness and quality of proteomes in UniProt, by looking at the sizes of taxonomically close proteomes. Possible values are 'Standard', 'Close to Standard' and 'Outlier'.</p> Close to standard (high)

The domestic dog (Canis lupus familiaris or Canis familiaris) is a subspecies of the gray wolf (Canis lupus). As the first animal to be domesticated (15,000-33,000 years ago) since then it has played an important role in the history of human civilization. In hunter-gatherer societies dogs hunted together with people and protected them. Nowadays they also assist in helping police and military, and aiding handicapped patients. Apart from that, dogs are kept worldwide as pets. Approximately 400 separate breeds are known, including those as diminutive as the Chihuahua and as massive as the Irish wolfhound.

The genome sequence was released in 2005. However, the effort to complete the annotation of the protein-coding and non-protein-coding gene sets is still going on to fully exploit this model organism. The domestic dog is studied for genetics to decipher phenotype/genotype relationships as well as for human and veterinary medicine. The dog genome has 39 chromosomes containing 2.4 Gb and 25,000 protein-coding genes.

Componentsi <p>Genomic components encoding the proteome</p>

Component nameGenome Accession(s)
Component representationProteins
Chromosome 12717
Chromosome 21773
Chromosome 31227
Chromosome 41308
Chromosome 52203
Chromosome 62052
Chromosome 71565
Chromosome 81471
Chromosome 92344
Chromosome 101470
Chromosome 111255
Chromosome 121280
Chromosome 13869
Chromosome 14872
Chromosome 151133
Chromosome 171322
Chromosome 16970
Chromosome 181463
Chromosome 19443
Chromosome 201991
Chromosome 211053
Chromosome 22510
Chromosome 23803
Chromosome 241124
Chromosome 25979
Chromosome 261076
Chromosome 271227
Chromosome 28850
Chromosome 29487
Chromosome 30987
Chromosome 31477
Chromosome 32549
Chromosome 33481
Chromosome 34515
Chromosome 35402
Chromosome 36439
Chromosome 37542
Chromosome 38470
Chromosome X1797
Unplaced
871
Mitochondrion15

Publications

  1. "The complete nucleotide sequence of the domestic dog (Canis familiaris) mitochondrial genome."
    Kim K.S., Lee S.E., Jeong H.W., Ha J.H.
    Mol. Phylogenet. Evol. 10:210-220(1998) [PubMed] [Europe PMC] [Abstract]
  2. "Genome sequence, comparative analysis and haplotype structure of the domestic dog."
    Lindblad-Toh K., Wade C.M., Mikkelsen T.S., Karlsson E.K., Jaffe D.B., Kamal M., Clamp M., Chang J.L., Kulbokas E.J. III, Zody M.C., Mauceli E., Xie X., Breen M., Wayne R.K., Ostrander E.A., Ponting C.P., Galibert F., Smith D.R.
    Lander E.S.
    Nature 438:803-819(2005) [PubMed] [Europe PMC] [Abstract]
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