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Overview

StatusReference proteome
Proteinsi <p>Number of protein entries associated with this proteome: UniProtKB entries for regular proteomes or UniParc entries for redundant proteomes (<a href="/help/proteome%5Fredundancy">more...</a>)</p> 43,621
Gene counti <p>This is the total number of unique genes found in the proteome set, algorithmically computed. For each gene, a single representative protein sequence is chosen from the proteome. Where possible, reviewed (Swiss-Prot) protein sequences are chosen as the representatives.</p> - Download one protein sequence per gene (FASTA)
Proteome IDi <p>The proteome identifier (UPID) is the unique identifier assigned to the set of proteins that constitute the <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a>. It consists of the characters 'UP' followed by 9 digits, is stable across releases and can therefore be used to cite a UniProt proteome.<p><a href='/help/proteome_id' target='_top'>More...</a></p>UP000002254
Taxonomy9615 - Canis lupus familiaris
StrainBoxer
Genome assembly and annotationi <p>Identifier for the genome assembly (<a href="https://www.ensembl.org/Help/Faq?id=216">more...</a>)</p> GCA_000002285.4 from Ensembl full
Buscoi <p>The Benchmarking Universal Single-Copy Ortholog (BUSCO) assessment tool is used, for eukaryotic and bacterial proteomes, to provide quantitative measures of UniProt proteome data completeness in terms of expected gene content. BUSCO scores include percentages of complete (C) single-copy (S) genes, complete (C) duplicated (D) genes, fragmented (F) and missing (M) genes, as well as the total number of orthologous clusters (n) used in the BUSCO assessment, and the name of the taxonomic lineage dataset used.</p> C:94.5%[S:45.3%,D:49.2%],F:1.1%,M:4.4%,n:14502 carnivora_odb10
Completenessi <p>Complete Proteome Detector (CPD) is an algorithm which employs statistical evaluation of the completeness and quality of proteomes in UniProt, by looking at the sizes of taxonomically close proteomes. Possible values are 'Standard', 'Close to Standard' and 'Outlier'.</p> Close to standard (high value)

The domestic dog (Canis lupus familiaris or Canis familiaris) is a subspecies of the gray wolf (Canis lupus). As the first animal to be domesticated (15,000-33,000 years ago) since then it has played an important role in the history of human civilization. In hunter-gatherer societies dogs hunted together with people and protected them. Nowadays they also assist in helping police and military, and aiding handicapped patients. Apart from that, dogs are kept worldwide as pets. Approximately 400 separate breeds are known, including those as diminutive as the Chihuahua and as massive as the Irish wolfhound.

The genome sequence was released in 2005. However, the effort to complete the annotation of the protein-coding and non-protein-coding gene sets is still going on to fully exploit this model organism. The domestic dog is studied for genetics to decipher phenotype/genotype relationships as well as for human and veterinary medicine. The dog genome has 39 chromosomes containing 2.4 Gb and 25,000 protein-coding genes.

Componentsi <p>Genomic components encoding the proteome</p>

Component nameGenome Accession(s)
Component representationProteins
Chromosome 12623
Chromosome 21666
Chromosome 31165
Chromosome 41212
Chromosome 52100
Chromosome 61929
Chromosome 71487
Chromosome 81343
Chromosome 92284
Chromosome 101403
Chromosome 111157
Chromosome 121202
Chromosome 13875
Chromosome 14816
Chromosome 151070
Chromosome 171235
Chromosome 161014
Chromosome 181557
Chromosome 19441
Chromosome 201916
Chromosome 21957
Chromosome 22481
Chromosome 23708
Chromosome 241079
Chromosome 25923
Chromosome 261052
Chromosome 271116
Chromosome 28864
Chromosome 29446
Chromosome 30894
Chromosome 31448
Chromosome 32504
Chromosome 33495
Chromosome 34489
Chromosome 35402
Chromosome 36401
Chromosome 37504
Chromosome 38495
Chromosome X1669
Unplaced
1187
Mitochondrion13

Publications

  1. "The complete nucleotide sequence of the domestic dog (Canis familiaris) mitochondrial genome."
    Kim K.S., Lee S.E., Jeong H.W., Ha J.H.
    Mol. Phylogenet. Evol. 10:210-220(1998) [PubMed] [Europe PMC] [Abstract]
  2. "Genome sequence, comparative analysis and haplotype structure of the domestic dog."
    Lindblad-Toh K., Wade C.M., Mikkelsen T.S., Karlsson E.K., Jaffe D.B., Kamal M., Clamp M., Chang J.L., Kulbokas E.J. III, Zody M.C., Mauceli E., Xie X., Breen M., Wayne R.K., Ostrander E.A., Ponting C.P., Galibert F., Smith D.R.
    Lander E.S.
    Nature 438:803-819(2005) [PubMed] [Europe PMC] [Abstract]
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