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Overview

StatusReference proteome
Proteinsi25,493
Gene counti <p>This is the total number of unique genes found in the proteome set, algorithmically computed. For each gene, a single representative protein sequence is chosen from the proteome. Where possible, reviewed (Swiss-Prot) protein sequences are chosen as the representatives.</p> - Download one protein sequence per gene (FASTA)
Proteome IDi <p>The proteome identifier (UPID) is the unique identifier assigned to the set of proteins that constitute the <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a>. It consists of the characters ‘UP’ followed by 9 digits, is stable across releases and can therefore be used to cite a UniProt proteome.<p><a href='/help/proteome_id' target='_top'>More...</a></p>UP000002254
Taxonomy9615 - Canis lupus familiaris
StrainBoxer
Last modifiedNovember 15, 2018
Genome assembly and annotationi GCA_000002285.2 from Ensembl

The domestic dog (Canis lupus familiaris or Canis familiaris) is a subspecies of the gray wolf (Canis lupus). As the first animal to be domesticated (15,000-33,000 years ago) since then it has played an important role in the history of human civilization. In hunter-gatherer societies dogs hunted together with people and protected them. Nowadays they also assist in helping police and military, and aiding handicapped patients. Apart from that, dogs are kept worldwide as pets. Approximately 400 separate breeds are known, including those as diminutive as the Chihuahua and as massive as the Irish wolfhound.

The genome sequence was released in 2005. However, the effort to complete the annotation of the protein-coding and non-protein-coding gene sets is still going on to fully exploit this model organism. The domestic dog is studied for genetics to decipher phenotype/genotype relationships as well as for human and veterinary medicine. The dog genome has 39 chromosomes containing 2.4 Gb and 25,000 protein-coding genes.

Componentsi <p>Genomic components encoding the proteome</p>

Component nameGenome Accession(s)
Proteins
Chromosome 11549
Chromosome 2946
Chromosome 3623
Chromosome 4690
Chromosome 51265
Chromosome 61116
Chromosome 7849
Chromosome 8760
Chromosome 91425
Chromosome 10826
Chromosome 11697
Chromosome 12722
Chromosome 13487
Chromosome 14441
Chromosome 15613
Chromosome 17762
Chromosome 16551
Chromosome 18896
Chromosome 19246
Chromosome 201142
Chromosome 21585
Chromosome 22282
Chromosome 23416
Chromosome 24642
Chromosome 25504
Chromosome 26609
Chromosome 27659
Chromosome 28481
Chromosome 29233
Chromosome 30515
Chromosome 31290
Chromosome 32269
Chromosome 33283
Chromosome 34296
Chromosome 35249
Chromosome 36217
Chromosome 37303
Chromosome 38253
Chromosome X1015
Unplaced
792
Mitochondrion15

Publications

  1. "Genome sequence, comparative analysis and haplotype structure of the domestic dog."
    Lindblad-Toh K., Wade C.M., Mikkelsen T.S., Karlsson E.K., Jaffe D.B., Kamal M., Clamp M., Chang J.L., Kulbokas E.J. III, Zody M.C., Mauceli E., Xie X., Breen M., Wayne R.K., Ostrander E.A., Ponting C.P., Galibert F., Smith D.R.
    Lander E.S.
    Nature 2005:803-819(2005) [PubMed] [Europe PMC] [Abstract]
  2. "The complete nucleotide sequence of the domestic dog (Canis familiaris) mitochondrial genome."
    Kim K.S., Lee S.E., Jeong H.W., Ha J.H.
    Mol. Phylogenet. Evol. 1998:210-220(1998) [PubMed] [Europe PMC] [Abstract]
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