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StatusReference proteome
Proteinsi <p>Number of protein entries associated with this proteome: UniProtKB entries for regular proteomes or UniParc entries for redundant proteomes (<a href="/help/proteome%5Fredundancy">more...</a>)</p> 45,350
Gene counti <p>This is the total number of unique genes found in the proteome set, algorithmically computed. For each gene, a single representative protein sequence is chosen from the proteome. Where possible, reviewed (Swiss-Prot) protein sequences are chosen as the representatives.</p> - Download one protein sequence per gene (FASTA)
Proteome IDi <p>The proteome identifier (UPID) is the unique identifier assigned to the set of proteins that constitute the <a href="">proteome</a>. It consists of the characters 'UP' followed by 9 digits, is stable across releases and can therefore be used to cite a UniProt proteome.<p><a href='/help/proteome_id' target='_top'>More...</a></p>UP000002254
Taxonomy9615 - Canis lupus familiaris
Last modifiedJanuary 15, 2020
Genome assembly and annotationi <p>Identifier for the genome assembly (<a href="">more...</a>)</p> GCA_000002285.2 from Ensembl full
CompletenessClose to Standard

The domestic dog (Canis lupus familiaris or Canis familiaris) is a subspecies of the gray wolf (Canis lupus). As the first animal to be domesticated (15,000-33,000 years ago) since then it has played an important role in the history of human civilization. In hunter-gatherer societies dogs hunted together with people and protected them. Nowadays they also assist in helping police and military, and aiding handicapped patients. Apart from that, dogs are kept worldwide as pets. Approximately 400 separate breeds are known, including those as diminutive as the Chihuahua and as massive as the Irish wolfhound.

The genome sequence was released in 2005. However, the effort to complete the annotation of the protein-coding and non-protein-coding gene sets is still going on to fully exploit this model organism. The domestic dog is studied for genetics to decipher phenotype/genotype relationships as well as for human and veterinary medicine. The dog genome has 39 chromosomes containing 2.4 Gb and 25,000 protein-coding genes.

Componentsi <p>Genomic components encoding the proteome</p>

Component nameGenome Accession(s)
Component representationProteins
Chromosome 12717
Chromosome 21771
Chromosome 31227
Chromosome 41306
Chromosome 52202
Chromosome 62052
Chromosome 71563
Chromosome 81470
Chromosome 92344
Chromosome 101470
Chromosome 111254
Chromosome 121279
Chromosome 13866
Chromosome 14872
Chromosome 151133
Chromosome 171319
Chromosome 16968
Chromosome 181461
Chromosome 19443
Chromosome 201989
Chromosome 211051
Chromosome 22510
Chromosome 23803
Chromosome 241122
Chromosome 25978
Chromosome 261075
Chromosome 271226
Chromosome 28850
Chromosome 29487
Chromosome 30986
Chromosome 31476
Chromosome 32549
Chromosome 33481
Chromosome 34515
Chromosome 35401
Chromosome 36439
Chromosome 37540
Chromosome 38470
Chromosome X1793


  1. "Genome sequence, comparative analysis and haplotype structure of the domestic dog."
    Lindblad-Toh K., Wade C.M., Mikkelsen T.S., Karlsson E.K., Jaffe D.B., Kamal M., Clamp M., Chang J.L., Kulbokas E.J. III, Zody M.C., Mauceli E., Xie X., Breen M., Wayne R.K., Ostrander E.A., Ponting C.P., Galibert F., Smith D.R.
    Lander E.S.
    Nature 438:803-819(2005) [PubMed] [Europe PMC] [Abstract]
  2. "The complete nucleotide sequence of the domestic dog (Canis familiaris) mitochondrial genome."
    Kim K.S., Lee S.E., Jeong H.W., Ha J.H.
    Mol. Phylogenet. Evol. 10:210-220(1998) [PubMed] [Europe PMC] [Abstract]
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