Proteomes - Dictyostelium discoideum (Slime mold)
Overview
| Status | Reference proteome |
| Proteinsi | 12,746 |
| Proteome IDi | UP000002195 |
| Taxonomy | 44689 - Dictyostelium discoideum |
| Strain | AX4 |
| Last modified | October 14, 2018 |
| Genome assembly and annotationi | GCA_000004695.1 from ENA/EMBL |
Dictyostelium discoideum, commonly known as slime mold, is a species of soil-living amoeba. It has the remarkable ability to switch from a solitary to a multicellular form. Under certain conditions, such as starvation, individuals aggregate and differentiate to generate a spore-releasing fruiting body. Since it is relatively easy to cultivate and manipulate in the laboratory, D. discoideum is a popular eukaryote model organism for researchers studying basic cellular processes such as chemotaxis, phagocytosis, apoptosis, signal transduction and cell differentiation.
The genome was sequenced in 2005, has a size of 34 Mb, and contains approximately 12,500 protein-coding genes. It has an unusually high repeat number and is also AT-rich (approximately 78%), making sequencing and assembly particularly challenging.
Componentsi
| Chromosome 1 | 1893 | ||
| Chromosome 2 | 2957 | ||
| Chromosome 3 | 2427 | ||
| Chromosome 4 | 2074 | ||
| Chromosome 5 | 1920 | ||
| Chromosome 6 | 1354 | ||
| Unassembled WGS sequence | 4196 | ||
| Mitochondrion | 42 |
Publications
- "The mitochondrial DNA of Dictyostelium discoideum: complete sequence, gene content and genome organization."
Ogawa S., Yoshino R., Angata K., Iwamoto M., Pi M., Kuroe K., Matsuo K., Morio T., Urushihara H., Yanagisawa K., Tanaka Y.
Mol. Gen. Genet. 2000:514-519(2000) [PubMed] [Europe PMC] [Abstract] - "Sequence and analysis of chromosome 2 of Dictyostelium discoideum."
Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T., Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R., Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A., Noegel A.A.
Nature 2002:79-85(2002) [PubMed] [Europe PMC] [Abstract] - "The genome of the social amoeba Dictyostelium discoideum."
Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. Kuspa A.
Nature 2005:43-57(2005) [PubMed] [Europe PMC] [Abstract]
