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Overview

StatusReference proteome
Proteinsi <p>Identifier for the genome assembly (<a href="https://www.ensembl.org/Help/Faq?id=216">more...</a>)</p> 3,723
Gene counti <p>This is the total number of unique genes found in the proteome set, algorithmically computed. For each gene, a single representative protein sequence is chosen from the proteome. Where possible, reviewed (Swiss-Prot) protein sequences are chosen as the representatives.</p> - Download one protein sequence per gene (FASTA)
Proteome IDi <p>The proteome identifier (UPID) is the unique identifier assigned to the set of proteins that constitute the <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a>. It consists of the characters ‘UP’ followed by 9 digits, is stable across releases and can therefore be used to cite a UniProt proteome.<p><a href='/help/proteome_id' target='_top'>More...</a></p>UP000001847
Taxonomy456481 - Leptospira biflexa serovar Patoc (strain Patoc 1 / ATCC 23582 / Paris)
StrainPatoc 1 / ATCC 23582 / Paris
Last modifiedNovember 9, 2018
Genome assembly and annotationi <p>Identifier for the genome assembly (<a href="https://www.ensembl.org/Help/Faq?id=216">more...</a>)</p> GCA_000017685.1 from ENA/EMBL
Pan proteomei <p>A pan proteome is the full set of proteins thought to be expressed by a group of highly related organisms (e.g. multiple strains of the same bacterial species).<p><a href='/help/pan_proteomes' target='_top'>More...</a></p> This proteome is part of the Leptospira biflexa serovar Patoc (strain Patoc 1 / ATCC 23582 / Paris) pan proteome (fasta)

Leptospirosis is one of the most common zoonotic diseases in the world, resulting in high morbidity and mortality in humans and affecting global livestock production. Most infections are caused by either L.borgpetersenii or L.interrogans, bacteria that vary in their distribution in nature and rely on different modes of transmission. L.borgpetersenii uses a host-to-host mode of transmission, whereas L.interrogans is usually acquired from contaminated surface water.

Leptospira biflexa is a free-living, saprophytic, aquatic spirochete. Its sequence will provide insights the differences between saprophytic and pathogenic species. L. biflexa serovar Patoc strain Patoc1, was initially isolated from stream water. Two strains that have been maintained separately for 17 years have been sequenced. One was maintained in the collection of the National Reference Center of Leptospira (Institut Pasteur, Paris, France) and designated the Paris strain; the second strain was derived from the same source but kept in the culture collection at the National Animal Disease Center (NADC), Ames, IA since 1990 and is designated the Ames strain (LEPBA).

Componentsi <p>Genomic components encoding the proteome</p>

Component nameGenome Accession(s)
Proteins
Chromosome I3388
Chromosome II276
Plasmid p7459

Publications

  1. "Genome sequence of the saprophyte Leptospira biflexa provides insights into the evolution of Leptospira and the pathogenesis of leptospirosis."
    Picardeau M., Bulach D.M., Bouchier C., Zuerner R.L., Zidane N., Wilson P.J., Creno S., Kuczek E.S., Bommezzadri S., Davis J.C., McGrath A., Johnson M.J., Boursaux-Eude C., Seemann T., Rouy Z., Coppel R.L., Rood J.I., Lajus A.
    Adler B.
    PLoS ONE 2008:E1607-E1607(2008) [PubMed] [Europe PMC] [Abstract]
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