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Gene counti <p>This is the total number of unique genes found in the proteome set, algorithmically computed. For each gene, a single representative protein sequence is chosen from the proteome. Where possible, reviewed (Swiss-Prot) protein sequences are chosen as the representatives.</p> - Download one protein sequence per gene (FASTA)
Proteome IDi <p>The proteome identifier (UPID) is the unique identifier assigned to the set of proteins that constitute the <a href="">proteome</a>. It consists of the characters ‘UP’ followed by 9 digits, is stable across releases and can therefore be used to cite a UniProt proteome.<p><a href='/help/proteome_id' target='_top'>More...</a></p>UP000001748
Taxonomy546272 - Brucella melitensis biotype 2 (strain ATCC 23457)
StrainATCC 23457
Last modifiedNovember 9, 2018
Genome assembly and annotationi GCA_000022625.1 from ENA/EMBL
Pan proteomei <p>A pan proteome is the full set of proteins thought to be expressed by a group of highly related organisms (e.g. multiple strains of the same bacterial species).<p><a href='/help/pan_proteomes' target='_top'>More...</a></p> This proteome is part of the Brucella abortus (strain 2308) pan proteome (fasta)

The genus Brucella is comprised mostly of mammalian pathogens, which due to their low infectious does, aerosol transmission and treatment difficulty are classified as potential bioterrorism agents. Brucellosis is a major infectious disease for both human and animals. Several Brucella species (B.abortus, B.melitensis and B.suis) have been isolated from many different animals. All three Brucella species cause a severe human disease characterized in its acute phase by undulant fever and in its chronic phase by damage of different organs. Brucellosis is a major problem in the Mediterranean region and parts of Asia, Africa and Latin America. When the infection is localized to the brain or the heart, it can result in a fatal meningitidis or fatal endocarditis, respectively. Brucella melitensis is a facultative intracellular bacterial pathogen that causes abortion in goats and sheep and undulant fever in humans. The disease is transmitted to human by consumption of nonpasteurized milk and milk products or by direct contact with infected animals and carcasses. Although Brucellae contain a large set of flagellar genes, they display a species-specific gene inactivation and consequently are nonmotile.

Strain 63/9, isolate 84, corresponding to ATCC 23457, is the type strain for this biovar. It was obtained from human blood and bone marrow samples (PubMed 11136777).

Componentsi <p>Genomic components encoding the proteome</p>

Component nameGenome Accession(s)
Chromosome I2055
Chromosome II1072


  1. "Brucella melitensis ATCC 23457 whole genome shotgun sequencing project."
    Setubal J.C., Boyle S., Crasta O.R., Gillespie J.J., Kenyon R.W., Lu J., Mane S., Nagrani S., Shallom J.M., Shallom S., Shukla M., Snyder E.E., Sobral B.W., Wattam A.R., Will R., Williams K., Yoo H., Munk C.
    Brettin T.S.
    Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases
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Main funding by: National Institutes of Health

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