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StatusReference proteome
Proteinsi <p>Number of protein entries associated with this proteome: UniProtKB entries for regular proteomes or UniParc entries for redundant proteomes (<a href="/help/proteome%5Fredundancy">more...</a>)</p> 9,214
Gene counti <p>This is the total number of unique genes found in the proteome set, algorithmically computed. For each gene, a single representative protein sequence is chosen from the proteome. Where possible, reviewed (Swiss-Prot) protein sequences are chosen as the representatives.</p> - Download one protein sequence per gene (FASTA)
Proteome IDi <p>The proteome identifier (UPID) is the unique identifier assigned to the set of proteins that constitute the <a href="">proteome</a>. It consists of the characters 'UP' followed by 9 digits, is stable across releases and can therefore be used to cite a UniProt proteome.<p><a href='/help/proteome_id' target='_top'>More...</a></p>UP000001631
Taxonomy447093 - Ajellomyces capsulatus (strain G186AR / H82 / ATCC MYA-2454 / RMSCC 2432)
StrainG186AR / H82 / ATCC MYA-2454 / RMSCC 2432
Last modifiedJune 28, 2020
Genome assembly and annotationi <p>Identifier for the genome assembly (<a href="">more...</a>)</p> GCA_000150115.1 from ENA/EMBL full

Ajellomyces capsulatus also known as Histoplasma capsulatum is a thermal dimorphic fungus that causes histoplasmosis, a potentially fatal disease of the lungs. The disease was first discovered by Samuel Darling in 1903, hence its other common name, Darling's disease fungus.

In moist soil that is rich in bird or bat guano at 25C, H. capsulatum exists in a filamentous mycelia form. Infection can arise from disturbing spore-rich soil. Spores are especially prevalent in the Ohio and Mississippi river valley regions. Outbreaks have been seen after earthquakes as spores are thrown into the air by the violent movement of the earth. Once inhaled, the spores develop into a yeast-like growth form in response to the higher temperature.

Approximately 95% of cases of histoplasmosis are unapparent, subclinical or benign. Traditionally, positive identification required the yeast to be grown at 37C on enriched media, however culture identification by the exoantigen test is now the method of choice.

The Ajellomyces capsulatus genome was sequenced by The Broad Institute using Sanger shotgun sequencing (ENA: AAJI00000000.1). It is predicted to contain 9,313 protein-coding genes. The reference proteome for this species is comprised of the G186AR strain.

Componentsi <p>Genomic components encoding the proteome</p>

Component nameGenome Accession(s)
Component representationProteins
Unassembled WGS sequence9214
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Main funding by: National Institutes of Health

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