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Overview

StatusReference proteome
Proteinsi <p>Number of protein entries associated with this proteome: UniProtKB entries for regular proteomes or UniParc entries for redundant proteomes (<a href="/help/proteome%5Fredundancy">more...</a>)</p> 5,388
Gene counti <p>This is the total number of unique genes found in the proteome set, algorithmically computed. For each gene, a single representative protein sequence is chosen from the proteome. Where possible, reviewed (Swiss-Prot) protein sequences are chosen as the representatives.</p> - Download one protein sequence per gene (FASTA)
Proteome IDi <p>The proteome identifier (UPID) is the unique identifier assigned to the set of proteins that constitute the <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a>. It consists of the characters 'UP' followed by 9 digits, is stable across releases and can therefore be used to cite a UniProt proteome.<p><a href='/help/proteome_id' target='_top'>More...</a></p>UP000001450
Taxonomy36329 - Plasmodium falciparum (isolate 3D7)
StrainIsolate 3D7
Last modifiedJanuary 29, 2021
Genome assembly and annotationi <p>Identifier for the genome assembly (<a href="https://www.ensembl.org/Help/Faq?id=216">more...</a>)</p> GCA_000002765.3 from ENA/EMBL full
Buscoi <p>The Benchmarking Universal Single-Copy Ortholog (BUSCO) assessment tool is used, for eukaryotic and bacterial proteomes, to provide quantitative measures of UniProt proteome data completeness in terms of expected gene content. BUSCO scores include percentages of complete (C) single-copy (S) genes, complete (C) duplicated (D) genes, fragmented (F) and missing (F) genes, as well as the total number of orthologous clusters (n) used in the BUSCO assessment.</p> C:99.1%[S:98%,D:1.1%],F:0%,M:0.9%,n:3642 plasmodium_odb10
Completenessi <p>Complete Proteome Detector (CPD) is an algorithm which employs statistical evaluation of the completeness and quality of proteomes in UniProt, by looking at the sizes of taxonomically close proteomes. Possible values are 'Standard', 'Close to Standard' and 'Outlier'.</p> Standard

Plasmodium falciparum is the malarial parasite most dangerous to humans, accounting for over 90% of all malarial deaths. It is transmitted by the female Anopheles mosquito. It was the first species of the genus Plasmodium to be sequenced at The Sanger Center, as part of the ongoing malaria genome sequencing project. Its genome is notable for an exceptionally low GC content of under 20%. In other respects, the genome has a similar size (23.3 Mb) and gene count (about 5300) to other species of malarial parasites.

Componentsi <p>Genomic components encoding the proteome</p>

Component nameGenome Accession(s)
Component representationProteins
Chromosome 1133
Chromosome 3240
Chromosome 4235
Chromosome 5313
Chromosome 6318
Chromosome 7294
Chromosome 8319
Chromosome 9383
Chromosome 13700
Mitochondrion3
Apicoplast A7
Apicoplast B23
Chromosome 2217
Chromosome 10409
Chromosome 11478
Chromosome 12531
Chromosome: api10
Chromosome 14773
Chromosome: mit2

Publications

  1. "Complete gene map of the plastid-like DNA of the malaria parasite Plasmodium falciparum."
    Wilson R.J.M., Denny P.W., Preiser P.R., Rangachari K., Roberts K., Roy A., Whyte A., Strath M., Moore D.J., Moore P.W., Williamson D.H.
    J. Mol. Biol. 261:155-172(1996) [PubMed] [Europe PMC] [Abstract]
  2. "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13."
    Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D., Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K., Buckee C.O., Burrows C., Cherevach I., Chillingworth C., Chillingworth T., Christodoulou Z.
    Barrell B.G.
    Nature 419:527-531(2002) [PubMed] [Europe PMC] [Abstract]
  3. Pathogen Informatics

    Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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