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StatusReference proteome
Gene counti - Download one protein sequence per gene (FASTA)
Proteome IDiUP000001300
Taxonomy284591 - Yarrowia lipolytica (strain CLIB 122 / E 150)
StrainCLIB 122 / E 150
Last modifiedFebruary 27, 2018
Genome assembly and annotationi GCA_000002525.1 from ENA/EMBL
Pan proteomei This proteome is part of the Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica) pan proteome (fasta)

Yarrowia lipolytica is a methane-using yeast which assimilates hydrocarbons and produces citric acid from n-alkanes, vegetable oils or glucose under aerobic conditions. Yarrowia lipolytica is routinely isolated from different food media (ie.cheeses, sausages)It is a hemiascomycetous yeast and these yeasts represent a homogeneous phylogenetic group of eukaryotes with a relatively large diversity at physiological and ecological levels. With their relatively small and compact genomes, yeasts offer a unique opportunity to explore eukaryotic genome evolution by comparative analysis of several species. Yeasts are widely used as cell factories, for the production of beer, wine and bread and more recently of various metabolic products such as vitamins, ethanol, citric acid, lipids, and for assimilation of hydrocarbons ie. Yarrowia lipolytica. Complete sequencing and comparison of four hemiascomycetous yeasts has been undertaken these are: Candida glabrata, Kluyveromyces lactis , Debaryomyces hansenii , Yarrowia lipolytica. They were selected on the basis of their phylogenetic positions and their specific interest as human pathogens, or as industrially or environmentally important yeasts. Yarrowia lipolytica is very distantly related to the rest of the yeasts; instead it shares a number of common properties with filamentous fungi. For each species, the haploid type strain was sequenced. Of importance for evolutionary studies, the four yeast species display different mechanisms of sexuality. Yarrowia lipolytica has a haplo-diplontic cycle (that is, it alternates between haploid and diploid phases of similar importance). This work, which represents the first multispecies exploration of genome evolution across an entire eukaryotic phylum, reveals the variety of events and mechanisms that have taken place, and shouldallow useful comparisons with other phyla of multicellular organisms when more genome sequences are determined.


Component nameGenome Accession(s)
Chromosome A686
Chromosome B948
Chromosome F1319
Chromosome E1465
Chromosome C926
Chromosome D1100
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Main funding by: National Institutes of Health

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