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StatusReference proteome
Proteinsi <p>Number of protein entries associated with this proteome: UniProtKB entries for regular proteomes or UniParc entries for redundant proteomes (<a href="/help/proteome%5Fredundancy">more...</a>)</p> 5,418
Gene counti <p>This is the total number of unique genes found in the proteome set, algorithmically computed. For each gene, a single representative protein sequence is chosen from the proteome. Where possible, reviewed (Swiss-Prot) protein sequences are chosen as the representatives.</p> - Download one protein sequence per gene (FASTA)
Proteome IDi <p>The proteome identifier (UPID) is the unique identifier assigned to the set of proteins that constitute the <a href="">proteome</a>. It consists of the characters 'UP' followed by 9 digits, is stable across releases and can therefore be used to cite a UniProt proteome.<p><a href='/help/proteome_id' target='_top'>More...</a></p>UP000001190
Taxonomy216594 - Mycobacterium marinum (strain ATCC BAA-535 / M)
StrainATCC BAA-535 / M
Last modifiedOctober 20, 2020
Genome assembly and annotationi <p>Identifier for the genome assembly (<a href="">more...</a>)</p> GCA_000018345.1 from ENA/EMBL full
Pan proteomei <p>A pan proteome is the full set of proteins thought to be expressed by a group of highly related organisms (e.g. multiple strains of the same bacterial species).<p><a href='/help/pan_proteomes' target='_top'>More...</a></p> This proteome is part of the Mycobacterium marinum (strain ATCC BAA-535 / M) pan proteome (fasta)
Buscoi <p>The Benchmarking Universal Single-Copy Ortholog (BUSCO) assessment tool is used, for eukaryotic and bacterial proteomes, to provide quantitative measures of UniProt proteome data completeness in terms of expected gene content. BUSCO scores include percentages of complete (C) single-copy (S) genes, complete (C) duplicated (D) genes, fragmented (F) and missing (F) genes, as well as the total number of orthologous clusters (n) used in the BUSCO assessment.</p> C:99.9%[S:99.1%,D:0.8%],F:0%,M:0.1%,n:743 corynebacteriales_odb10
Completenessi <p>Complete Proteome Detector (CPD) is an algorithm which employs statistical evaluation of the completeness and quality of proteomes in UniProt, by looking at the sizes of taxonomically close proteomes. Possible values are 'Standard', 'Close to Standard' and 'Outlier'.</p> Standard

Mycobacterium marinum, a ubiquitous pathogen of fish and amphibia, is a near relative of Mycobacterium tuberculosis, the etiologic agent of tuberculosis in humans. It is Gram-positive, rod-shaped, facultative anaerobic bacterium commonly found in various aquatic environments around the world, including swimming pools and drinking water. In 1926, Joseph D. Aronson isolated a Mycobacterium from tubercles observed predominantly in the spleen and liver of diseased fish that had died in the Philadelphia Aquarium and named it M. marinum. It was subsequently shown to also be a human pathogen when it was isolated again much later in a swimming pool-associated outbreak of human granulomatous skin lesions, although in this report the Mycobacterium was mistakenly given a new species name, Mycobacterium balnei, a name that is no longer used. This bacterium causes a tuberculosis-like disease in frogs, fish and other poikilothermic animals, and a peripheral granulomatous disease in humans. M. marinum infection of humans, called fish tank or aquarium tank granuloma, typically occurs when M. marinum is inoculated through the skin by cuts and scratches following direct contact with an infected fish or contaminated aquatic environments. The ensuing granulomatous infection generally limited to the skin and soft tissues extremities is pathologically indistinguishable from M. tuberculosis dermal disease. Its optimal growth temperature is 35 degrees Celsius (in Middlebrook 7H9 medium). Its lower optimal growth temperature likely explains its causing systemic disease in poikilotherms animals and a superficial disease, restricted cooler extremities of the body, in warm-blooded animals. In contrast to M. tuberculosis, it is unable to reduce nitrate and produces characteristic bright yellow carotenoid pigments when exposed to light. These photochromogenic pigments protect it from UV damage in incident sunlight by reducing singlet oxygen species. It can form biofilms. Mycobacteria have an unusual outer membrane approximately 8nm thick, despite being considered Gram-positive. The outer membrane and the mycolic acid-arabinoglactan-peptidoglycan polymer form the cell wall, which constitutes an efficient permeability barrier in conjunction with the cell inner membrane.

Componentsi <p>Genomic components encoding the proteome</p>

Component nameGenome Accession(s)
Component representationProteins
Plasmid pMM2329
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Main funding by: National Institutes of Health

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