Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Overview

Proteinsi4,143
Gene counti <p>This is the total number of unique genes found in the proteome set, algorithmically computed. For each gene, a single representative protein sequence is chosen from the proteome. Where possible, reviewed (Swiss-Prot) protein sequences are chosen as the representatives.</p> - Download one protein sequence per gene (FASTA)
Proteome IDi <p>The proteome identifier (UPID) is the unique identifier assigned to the set of proteins that constitute the <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a>. It consists of the characters ‘UP’ followed by 9 digits, is stable across releases and can therefore be used to cite a UniProt proteome.<p><a href='/help/proteome_id' target='_top'>More...</a></p>UP000001030
Taxonomy344609 - Shigella boydii serotype 18 (strain CDC 3083-94 / BS512)
StrainCDC 3083-94 / BS512
Last modifiedDecember 12, 2018
Genome assembly and annotationi GCA_000020185.1 from ENA/EMBL
Pan proteomei <p>A pan proteome is the full set of proteins thought to be expressed by a group of highly related organisms (e.g. multiple strains of the same bacterial species).<p><a href='/help/pan_proteomes' target='_top'>More...</a></p> This proteome is part of the Escherichia coli (strain K12) pan proteome (fasta)

Shigella is a Gram-negative, non-sporulating, facultative anaerobe bacterium that causes dysentery or shigellosis in man. Shigella are highly invasive in the colon and the rectum, and are able to proliferate in the host cell cytoplasm, triggering an inflammatory reaction. Shigella was recognized as the etiologic agent for bacillary dysentery in the 1890's, and adopted as a genus in the 1950's and subgrouped into four species. However, a recent genetic study argues that Shigella emerged from multiple independent origins of E.coli 35,000-270,000 years ago and may not constitute a genus. S.boydii is mainly epidemic to the Indian subcontinent. Comparison of 20 E.coli/Shigella strains shows the core genome to be about 2000 genes while the pan-genome has over 18,000 genes. There are multiple, striking integration hotspots that are conserved across the genomes, corresponding to regions of abundant and parallel insertions and deletions of genetic material. Shigella boydii BS512 was originally isolated from a 12-year-old boy in Arizona, USA. It is serotype 18 and is a member of Group 1 as determined by sequence analysis. The virulence of S. boydii BS512 has been verified through in vitro experimentation via invasion of HeLa cells.

Componentsi <p>Genomic components encoding the proteome</p>

Component nameGenome Accession(s)
Proteins
Plasmid pBS512_23
Chromosome3867
Plasmid pBS512_211224
Plasmid pBS512_3352
Plasmid pBS512_710
Plasmid pBS512_54

Publications

  1. "Complete sequence of Shigella boydii serotype 18 strain BS512."
    Rasko D.A., Rosovitz M., Maurelli A.T., Myers G., Seshadri R., Cer R., Jiang L., Ravel J., Sebastian Y.
    Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again