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Overview

StatusReference proteome
Proteinsi2,041
Gene counti <p>This is the total number of unique genes found in the proteome set, algorithmically computed. For each gene, a single representative protein sequence is chosen from the proteome. Where possible, reviewed (Swiss-Prot) protein sequences are chosen as the representatives.</p> - Download one protein sequence per gene (FASTA)
Proteome IDi <p>The proteome identifier (UPID) is the unique identifier assigned to the set of proteins that constitute the <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a>. It consists of the characters ‘UP’ followed by 9 digits, is stable across releases and can therefore be used to cite a UniProt proteome.<p><a href='/help/proteome_id' target='_top'>More...</a></p>UP000000819
StrainGB-M1
Last modifiedNovember 9, 2018
Genome assembly and annotationi GCA_000091225.2 from ENA/EMBL
Pan proteomei <p>A pan proteome is the full set of proteins thought to be expressed by a group of highly related organisms (e.g. multiple strains of the same bacterial species).<p><a href='/help/pan_proteomes' target='_top'>More...</a></p> This proteome is part of the Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite) pan proteome (fasta)

Microsporidia are unicellular parasites that lack mitochondria and peroxisomes and are characterized by production of resistant spores. Encephalitozoon cuniculi is one of the 14 microsporidians that have been identified as human pathogens, causing various pathologies affecting the nervous system as well as the respiratory and digestive tracts. It can also infect a wide range of other hosts, being a major health issue for rabbits. Encephalitozoon cuniculi has a very small and specialized genome, which can be used as a tool for identifying genes that are involved in energy metabolism and in infections that parasites cause in humans.

The reference proteome for E. cuniculi is derived from the genome sequence published in 2001. The genome is remarkably compact, containing about 2.9Mb, with 1997 predicted protein-coding genes, organized into 11 linear chromosomes. Genome compaction is reflected by reduced intergenic spacers and by the shortness of most putative proteins relative to their eukaryote orthologs.

Componentsi <p>Genomic components encoding the proteome</p>

Component nameGenome Accession(s)
Proteins
Chromosome I145
Chromosome II169
Chromosome III166
Chromosome IV189
Chromosome V180
Chromosome VI183
Chromosome VII200
Chromosome VIII221
Chromosome IX221
Chromosome X200
Chromosome XI227

Publications

  1. "Sequence and analysis of chromosome I of the amitochondriate intracellular parasite Encephalitozoon cuniculi (Microspora)."
    Peyret P., Katinka M.D., Duprat S., Duffieux F., Barbe V., Barbazanges M., Weissenbach J., Saurin W., Vivares C.P.
    Genome Res. 2001:198-207(2001) [PubMed] [Europe PMC] [Abstract]
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