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Overview

StatusReference proteome
Proteinsi <p>Number of protein entries associated with this proteome: UniProtKB entries for regular proteomes or UniParc entries for redundant proteomes (<a href="/help/proteome%5Fredundancy">more...</a>)</p> 2,844
Gene counti <p>This is the total number of unique genes found in the proteome set, algorithmically computed. For each gene, a single representative protein sequence is chosen from the proteome. Where possible, reviewed (Swiss-Prot) protein sequences are chosen as the representatives.</p> - Download one protein sequence per gene (FASTA)
Proteome IDi <p>The proteome identifier (UPID) is the unique identifier assigned to the set of proteins that constitute the <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a>. It consists of the characters 'UP' followed by 9 digits, is stable across releases and can therefore be used to cite a UniProt proteome.<p><a href='/help/proteome_id' target='_top'>More...</a></p>UP000000817
Taxonomy169963 - Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
StrainATCC BAA-679 / EGD-e
Last modifiedJune 29, 2020
Genome assembly and annotationi <p>Identifier for the genome assembly (<a href="https://www.ensembl.org/Help/Faq?id=216">more...</a>)</p> GCA_000196035.1 from ENA/EMBL full
Pan proteomei <p>A pan proteome is the full set of proteins thought to be expressed by a group of highly related organisms (e.g. multiple strains of the same bacterial species).<p><a href='/help/pan_proteomes' target='_top'>More...</a></p> This proteome is part of the Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) pan proteome (fasta)
BuscoC:96.7%[S:96.2%,D:0.4%],F:0%,M:3.3%,n:450
CompletenessStandard

Gram-positive rods motile by a few peritrichous flagella. 1-10% of humans might be intestinal carriers of L.monocytogenes. It has been found in at least 37 mammalian species, both domestic and feral, as well as at least 17 species of birds and possibly some species of fish and shellfish. It can be isolated from soil, silage, and other environmental sources. L.monocytogenes is quite hardy and resists the deleterious effects of freezing, drying, and heat remarkably well for a bacterium that does not form spores. The manifestations of listeriosis include septicemia, meningitis (or meningoencephalitis), encephalitis, and intrauterine or cervical infections in pregnant women. Most listeriosis is caused by serotypes 4b, 1/2a and 1/2b, while serotype 4a is naturally avirulent, and hence has possibilities as a vaccine candidate.

EGD-e (UP000000817) is genetically highly distinct from EGD (UP000016703, with 29,016 single nucleotide polymorphisms [SNPs]) and 10403S (UP000001288, with 30,296 SNPs), and is more related to serovar 1/2c than 1/2a strains. EGD and 10403S strains are genetically very close (317 SNPs), however EGD has a point mutation in the transcriptional regulator PrfA (PrfA*), leading to constitutive expression of several major virulence genes. Adapted from PMID 24667708.

Componentsi <p>Genomic components encoding the proteome</p>

Component nameGenome Accession(s)
Component representationProteins
Chromosome2844
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Main funding by: National Institutes of Health

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