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Overview

Proteins1,596
Proteome IDiUP000000775
Taxonomy382638 - Helicobacter acinonychis (strain Sheeba)
StrainSheeba
Last modifiedFebruary 27, 2018
Genome assembly and annotationi GCA_000009305.1 from ENA/EMBL
Pan proteomei This proteome is part of the Helicobacter pylori (strain ATCC 700392 / 26695) pan proteome (fasta)

Helicobacter acinonychis strain Sheeba is the causative agent of severe gastritis in large felines such as tigers, lions and cheetahs. H. acinonychis arose 200000 years ago via a host jump of H.pylori from early humans. Its genome is made up of one chromosome and one plasmid. It possesses a large number of highly fragmented genes, many encoding outer membrane proteins. These genes could have been destroyed in order to bypass deleterious responses from the feline host immune system. Five genes are present that are involved in sialylation of cell surface carbohydrates and that were probably acquired by horizontal gene transfer.

Componentsi

DownloadView all proteins
Component nameGenome Accession(s)
Proteins
Chromosome1590
Plasmid pHac16

Publications

  1. "Who ate whom? Adaptive Helicobacter genomic changes that accompanied a host jump from early humans to large felines."
    Eppinger M., Baar C., Linz B., Raddatz G., Lanz C., Keller H., Morelli G., Gressmann H., Achtman M., Schuster S.C.
    PLoS Genet. 2006:1097-1110(2006) [PubMed] [Europe PMC] [Abstract]

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