Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Overview

Proteinsi977
Gene counti - Download one protein sequence per gene (FASTA)
Proteome IDiUP000000612
Taxonomy412418 - Borrelia recurrentis (strain A1)
StrainA1
Last modifiedFebruary 27, 2018
Genome assembly and annotationi GCA_000019705.1 from ENA/EMBL
Pan proteomei This proteome is part of the Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680) pan proteome (fasta)

Relapsing fever (RF) is a disease caused by several spirochetes of the genus Borrelia. Relapsing fever borrelioses are characterized by recurrent febrile episodes and spirochetemia. There are 2 forms; louse-borne relapsing fever (also known as urban or epidemic RF) is caused by Borrelia recurrentis, and is transmitted by the body louse Pediculus humanus humanus. It currently known in Ethiopia. Endemic tick-borne relapsing fever (TBRF) is a zoonotic disease transmitted worldwide by softbody ticks of the genus Ornithodoros. It is caused by at least 15 distinct Borrelia species throughout the world.

Borrelia recurrentis strain A1 was isolated from an adult with RF in Ethiopia. RF causes fewer relapses that TBRF but has a higher spontaneous mortality rate despite antibiotics. Previous work suggested that B.recurrentis was very closely related to B.duttonii; the current sequencing project suggests that in fact B.recurrentis should be considered a strain of B.duttonii that is undergoing considerable gene decay. Decay is probably due at least in part to mutated recA and mutS genes in A1. All 6 plasmids in strain A1 have a counterpart in B.duttonii strain Ly (BORDL).

Componentsi

Component nameGenome Accession(s)
Proteins
Chromosome799
Plasmid pl12491
Plasmid pl2317
Plasmid pl3317
Plasmid pl3515
Plasmid pl3719
Plasmid pl5328
Plasmid pl63

Publications

  1. "The genome of Borrelia recurrentis, the agent of deadly louse-borne relapsing fever, is a degraded subset of tick-borne Borrelia duttonii."
    Lescot M., Audic S., Robert C., Nguyen T.T., Blanc G., Cutler S.J., Wincker P., Couloux A., Claverie J.-M., Raoult D., Drancourt M.
    PLoS Genet. 2008:E1000185-E1000185(2008) [PubMed] [Europe PMC] [Abstract]
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again