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Overview

StatusReference proteome
Proteinsi54,188
Gene counti <p>This is the total number of unique genes found in the proteome set, algorithmically computed. For each gene, a single representative protein sequence is chosen from the proteome. Where possible, reviewed (Swiss-Prot) protein sequences are chosen as the representatives.</p> - Download one protein sequence per gene (FASTA)
Proteome IDi <p>The proteome identifier (UPID) is the unique identifier assigned to the set of proteins that constitute the <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a>. It consists of the characters ‘UP’ followed by 9 digits, is stable across releases and can therefore be used to cite a UniProt proteome.<p><a href='/help/proteome_id' target='_top'>More...</a></p>UP000000589
Taxonomy10090 - Mus musculus
StrainC57BL/6J
Last modifiedNovember 15, 2018
Genome assembly and annotationi GCA_000001635.8 from Ensembl

The house mouse (Mus musculus) is a common rodent that is distributed throughout the world. It has become a frequently used model for understanding human disease and development due to its small size, short life-cycle and rapid breeding cycle.

The mouse was the second mammal to have its genome sequenced. The mouse strain used for sequencing was C57BL/6J, which is the most widely used inbred strain. This strain is a permissive background for the expression of most mutations, but is resilient to many tumors.

C57BL/6J mice are susceptible to atherosclerosis, type 2 diabetes and diet-induced obesity. It also develops age-related hearing loss. 75% of the mouse genes are in 1:1 orthologous relationships to human genes and have most likely maintained their ancestral function in both species.

The reference proteome of Mus musculus is derived from the genome sequence of strain C57BL/6J that was published in 2009. The size of the genome is 2.6 Gb and it contains 20,210 predicted protein-coding genes.

Componentsi <p>Genomic components encoding the proteome</p>

Component nameGenome Accession(s)
Proteins
Chromosome 13156
Chromosome 23992
Chromosome 32499
Chromosome 42925
Chromosome 53464
Chromosome 62990
Chromosome 75011
Chromosome 82433
Chromosome 93211
Chromosome 102447
Chromosome 113518
Chromosome 121862
Chromosome 131981
Chromosome 142249
Chromosome 151992
Chromosome 161708
Chromosome 172526
Chromosome 181023
Chromosome 191429
Chromosome Y140
Chromosome X1750
Unplaced
1913
Mitochondrion13
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Main funding by: National Institutes of Health

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