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Overview

StatusReference proteome
Proteinsi53,857
Gene counti - Download one protein sequence per gene (FASTA)
Proteome IDiUP000000589
Taxonomy10090 - Mus musculus
StrainC57BL/6J
Last modifiedJuly 27, 2018
Genome assembly and annotationi GCA_000001635.8 from Ensembl

The house mouse (Mus musculus) is a common rodent that is distributed throughout the world. It has become a frequently used model for understanding human disease and development due to its small size, short life-cycle and rapid breeding cycle.

The mouse was the second mammal to have its genome sequenced. The mouse strain used for sequencing was C57BL/6J, which is the most widely used inbred strain. This strain is a permissive background for the expression of most mutations, but is resilient to many tumors.

C57BL/6J mice are susceptible to atherosclerosis, type 2 diabetes and diet-induced obesity. It also develops age-related hearing loss. 75% of the mouse genes are in 1:1 orthologous relationships to human genes and have most likely maintained their ancestral function in both species.

The reference proteome of Mus musculus is derived from the genome sequence of strain C57BL/6J that was published in 2009. The size of the genome is 2.6 Gb and it contains 20,210 predicted protein-coding genes.

Componentsi

Component nameGenome Accession(s)
Proteins
Chromosome 13156
Chromosome 23991
Chromosome 32492
Chromosome 42927
Chromosome 53443
Chromosome 62980
Chromosome 74942
Chromosome 82433
Chromosome 93219
Chromosome 102433
Chromosome 113516
Chromosome 121861
Chromosome 131981
Chromosome 142242
Chromosome 151992
Chromosome 161676
Chromosome 172251
Chromosome 181024
Chromosome 191426
Chromosome Y140
Chromosome X1748
Unplaced
2017
Mitochondrion13
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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