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StatusReference proteome
Proteinsi <p>Number of protein entries associated with this proteome: UniProtKB entries for regular proteomes or UniParc entries for redundant proteomes (<a href="/help/proteome%5Fredundancy">more...</a>)</p> 8,038
Gene counti <p>This is the total number of unique genes found in the proteome set, algorithmically computed. For each gene, a single representative protein sequence is chosen from the proteome. Where possible, reviewed (Swiss-Prot) protein sequences are chosen as the representatives.</p> - Download one protein sequence per gene (FASTA)
Proteome IDi <p>The proteome identifier (UPID) is the unique identifier assigned to the set of proteins that constitute the <a href="">proteome</a>. It consists of the characters 'UP' followed by 9 digits, is stable across releases and can therefore be used to cite a UniProt proteome.<p><a href='/help/proteome_id' target='_top'>More...</a></p>UP000000542
Taxonomy5664 - Leishmania major
Last modifiedMarch 7, 2021
Genome assembly and annotationi <p>Identifier for the genome assembly (<a href="">more...</a>)</p> GCA_000002725.2 from ENA/EMBL full
Buscoi <p>The Benchmarking Universal Single-Copy Ortholog (BUSCO) assessment tool is used, for eukaryotic and bacterial proteomes, to provide quantitative measures of UniProt proteome data completeness in terms of expected gene content. BUSCO scores include percentages of complete (C) single-copy (S) genes, complete (C) duplicated (D) genes, fragmented (F) and missing (F) genes, as well as the total number of orthologous clusters (n) used in the BUSCO assessment.</p> C:100%[S:100%,D:0%],F:0%,M:0%,n:130 euglenozoa_odb10
Completenessi <p>Complete Proteome Detector (CPD) is an algorithm which employs statistical evaluation of the completeness and quality of proteomes in UniProt, by looking at the sizes of taxonomically close proteomes. Possible values are 'Standard', 'Close to Standard' and 'Outlier'.</p> Standard

Leishmania is a genus of trypanosomatid parasites that are intracellular pathogens of the immune system and are the causative agents of the disease Leishmaniasis, which is an infectious disease that is transmitted by the bite of certain species of sand fly.

Over 20 Leishmania species can infect humans and cause a spectrum of diseases. The symptoms range from disfiguring cutaneous and mucocutaneous lesions to visceral disease affecting the hematopoietic organs. Leishmaniasis affects the populations of 88 tropical and subtropical countries worldwide, and there is currently no vaccine and few effective drugs for it.

Leishmania major is an Old World pathogen and the cause of cutaneous leishmaniasis mainly in North Africa, the Middle East, west India and Sudan.

The reference proteome of Leishmania major is derived from the genome sequence published in 2005. The size of the haploid genome is 33 Mb and consists of 36 chromosomes.

Componentsi <p>Genomic components encoding the proteome</p>

Component nameGenome Accession(s)
Component representationProteins
Chromosome 183
Chromosome 274
Chromosome 394
Chromosome 4123
Chromosome 5123
Chromosome 6133
Chromosome 7126
Chromosome 8124
Chromosome 9161
Chromosome 10139
Chromosome 11129
Chromosome 12140
Chromosome 13158
Chromosome 14152
Chromosome 15153
Chromosome 16168
Chromosome 17152
Chromosome 18166
Chromosome 19165
Chromosome 20175
Chromosome 21221
Chromosome 22164
Chromosome 23190
Chromosome 24235
Chromosome 25252
Chromosome 26267
Chromosome 27260
Chromosome 28311
Chromosome 29295
Chromosome 30378
Chromosome 31327
Chromosome 32407
Chromosome 33337
Chromosome 34433
Chromosome 35526
Chromosome 36723


  1. "The genome of the kinetoplastid parasite, Leishmania major."
    Ivens A.C., Peacock C.S., Worthey E.A., Murphy L., Aggarwal G., Berriman M., Sisk E., Rajandream M.A., Adlem E., Aert R., Anupama A., Apostolou Z., Attipoe P., Bason N., Bauser C., Beck A., Beverley S.M., Bianchettin G.
    Myler P.J.
    Science 309:436-442(2005) [PubMed] [Europe PMC] [Abstract]
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