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Proteinsi <p>Number of protein entries associated with this proteome: UniProtKB entries for regular proteomes or UniParc entries for redundant proteomes (<a href="/help/proteome%5Fredundancy">more...</a>)</p> 2,383
Gene counti <p>This is the total number of unique genes found in the proteome set, algorithmically computed. For each gene, a single representative protein sequence is chosen from the proteome. Where possible, reviewed (Swiss-Prot) protein sequences are chosen as the representatives.</p> - Download one protein sequence per gene (FASTA)
Proteome IDi <p>The proteome identifier (UPID) is the unique identifier assigned to the set of proteins that constitute the <a href="">proteome</a>. It consists of the characters 'UP' followed by 9 digits, is stable across releases and can therefore be used to cite a UniProt proteome.<p><a href='/help/proteome_id' target='_top'>More...</a></p>UP000000364
Taxonomy416870 - Lactococcus lactis subsp. cremoris (strain MG1363)
Genome assembly and annotationi <p>Identifier for the genome assembly (<a href="">more...</a>)</p> GCA_000009425.1 from ENA/EMBL full
Pan proteomei <p>A pan proteome is the full set of proteins thought to be expressed by a group of highly related organisms (e.g. multiple strains of the same bacterial species).<p><a href='/help/pan_proteomes' target='_top'>More...</a></p> This proteome is part of the Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis) pan proteome (fasta)
Buscoi <p>The Benchmarking Universal Single-Copy Ortholog (BUSCO) assessment tool is used, for eukaryotic and bacterial proteomes, to provide quantitative measures of UniProt proteome data completeness in terms of expected gene content. BUSCO scores include percentages of complete (C) single-copy (S) genes, complete (C) duplicated (D) genes, fragmented (F) and missing (M) genes, as well as the total number of orthologous clusters (n) used in the BUSCO assessment, and the name of the taxonomic lineage dataset used.</p> C:99.3%[S:99.3%,D:0%],F:0%,M:0.7%,n:402 lactobacillales_odb10
Completenessi <p>Complete Proteome Detector (CPD) is an algorithm which employs statistical evaluation of the completeness and quality of proteomes in UniProt, by looking at the sizes of taxonomically close proteomes. Possible values are 'Standard', 'Close to Standard' and 'Outlier'.</p> Standard

Lactococcus lactis subsp. cremoris MG1363, is the lactococcal strain most intensively studied throughout the world. It is a plasmid-free Lactococcus strain. It is not a natural inhabitant of the human gastrointestinal tract, but does survive passage through it, and has been used to deliver bioactive peptides to the gut. There are a number of mobile genetic elements in L. lactis MG1363, namely the unique sex factor, insertion elements, and the integration hotspot region. The latter enables L. lactis MG1363 to stably integrate laterally acquired DNA and has played a key role in the evolution of the genome of L. lactis MG1363 and related strains. It allowed L. lactis MG1363 to stably maintain a functional copy of the opp operon, which is essential for growth in milk. Forty seven of the genes present in L. lactis MG1363 but absent in L. lactis IL1403 are thought to be involved in carbohydrate metabolism and transport. Consequently L. lactis MG1363 displays a larger capability to grow on various sugars, especially those found in plant material, pointing to a plant associated biological niche for the ancestor of L. lactis MG1363. Lactococci are mesophilic lactic acid bacteria that were first isolated from green plants. However, today they are used extensively in food fermentations. These bacteria are selected for use in fermentations based on their metabolic stability, their resistance to bacteriophage, and their ability to produce unique compounds often from amino acid catabolism. The study of their physiology in adverse conditions such as low pH and high NaCl indicates that they adapt to these environments quickly and change their metabolism based on carbohydrate starvation. Recent genome studies and physical maps indicate that bacterial genomes are very dynamic. The importance of lactococci, specifically L. lactis subsp. cremoris, is demonstrated by its continual use in food fermentations. L. lactis subsp. cremoris strains are preferred over L. lactis subsp. lactis strains because of their superior contribution to product flavor via unique metabolic mechanisms.

Componentsi <p>Genomic components encoding the proteome</p>

Component nameGenome Accession(s)
Component representationProteins


  1. "The complete genome sequence of the lactic acid bacterial paradigm Lactococcus lactis subsp. cremoris MG1363."
    Wegmann U., O'Connell-Motherway M., Zomer A., Buist G., Shearman C., Canchaya C., Ventura M., Goesmann A., Gasson M.J., Kuipers O.P., van Sinderen D., Kok J.
    J. Bacteriol. 189:3256-3270(2007) [PubMed] [Europe PMC] [Abstract]
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