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Overview

Proteinsi4,327
Gene counti <p>This is the total number of unique genes found in the proteome set, algorithmically computed. For each gene, a single representative protein sequence is chosen from the proteome. Where possible, reviewed (Swiss-Prot) protein sequences are chosen as the representatives.</p> - Download one protein sequence per gene (FASTA)
Proteome IDi <p>The proteome identifier (UPID) is the unique identifier assigned to the set of proteins that constitute the <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a>. It consists of the characters ‘UP’ followed by 9 digits, is stable across releases and can therefore be used to cite a UniProt proteome.<p><a href='/help/proteome_id' target='_top'>More...</a></p>UP000000225
Taxonomy382245 - Aeromonas salmonicida (strain A449)
StrainA449
Last modifiedNovember 9, 2018
Genome assembly and annotationi GCA_000196395.1 from ENA/EMBL
Pan proteomei <p>A pan proteome is the full set of proteins thought to be expressed by a group of highly related organisms (e.g. multiple strains of the same bacterial species).<p><a href='/help/pan_proteomes' target='_top'>More...</a></p> This proteome is part of the Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / JCM 1027 / KCTC 2358 / NCIMB 9240) pan proteome (fasta)

Aeromonas salmonicida has been recognized as a pathogen of fish for over 100 years. In 1894 Emmerich and Weibel made the first report of its isolation during a disease outbreak at a Bavarian brown trout hatchery. The manifestations of the disease include furuncle-like swelling and, at a later stage, ulcerative lesions on infected trout. Since that time a number of subspecies of Aeromonas salmonicida have been recognized, although the taxonomy of the species is far from settled. While Aeromonas salmonicida was traditionally thought of as a pathogen of salmonids, global reports now confirm that this pathogen has been associated with clinical or covert disease in a variety of salmonid and non-salmonid species in freshwater, brackish water and sea water.

Aeromonas salmonicida (strain A449) was isolated from a brown trout in the Eure River, France in 1975 and harbors one chromosome and 5 plasmids. Comparison to the related A.hydrophilia ATCC 7966 (AERHH) show the presence of numerous insertion sequence, some of which are still active and various other mobile elements lreading to substantial genome rearrangements. A.salmonicida is no longer mobile and has also recently lost a type IV and type VI secretion systems, thus probably avoiding the host immune system. It seems to be undergoing genome decay and adaptation to its specific host (adapted from PMID 18801193).

Componentsi <p>Genomic components encoding the proteome</p>

Component nameGenome Accession(s)
Proteins
Chromosome3993
Plasmid pAsa18
Plasmid pAsa27
Plasmid pAsa39
Plasmid pAsa4171
Plasmid pAsa5149

Publications

  1. "The genome of Aeromonas salmonicida subsp. salmonicida A449: insights into the evolution of a fish pathogen."
    Reith M.E., Singh R.K., Curtis B., Boyd J.M., Bouevitch A., Kimball J., Munholland J., Murphy C., Sarty D., Williams J., Nash J.H., Johnson S.C., Brown L.L.
    BMC Genomics 2008:427-427(2008) [PubMed] [Europe PMC] [Abstract]
  2. "Three small, cryptic plasmids from Aeromonas salmonicida subsp. salmonicida A449."
    Boyd J., Williams J., Curtis B., Kozera C., Singh R., Reith M.
    Plasmid 2003:131-144(2003) [PubMed] [Europe PMC] [Abstract]
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