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Proteinsi <p>Number of protein entries associated with this proteome: UniProtKB entries for regular proteomes or UniParc entries for redundant proteomes (<a href="/help/proteome%5Fredundancy">more...</a>)</p> 4,327
Gene counti <p>This is the total number of unique genes found in the proteome set, algorithmically computed. For each gene, a single representative protein sequence is chosen from the proteome. Where possible, reviewed (Swiss-Prot) protein sequences are chosen as the representatives.</p> - Download one protein sequence per gene (FASTA)
Proteome IDi <p>The proteome identifier (UPID) is the unique identifier assigned to the set of proteins that constitute the <a href="">proteome</a>. It consists of the characters 'UP' followed by 9 digits, is stable across releases and can therefore be used to cite a UniProt proteome.<p><a href='/help/proteome_id' target='_top'>More...</a></p>UP000000225
Taxonomy382245 - Aeromonas salmonicida (strain A449)
Last modifiedJuly 21, 2020
Genome assembly and annotationi <p>Identifier for the genome assembly (<a href="">more...</a>)</p> GCA_000196395.1 from ENA/EMBL full
Pan proteomei <p>A pan proteome is the full set of proteins thought to be expressed by a group of highly related organisms (e.g. multiple strains of the same bacterial species).<p><a href='/help/pan_proteomes' target='_top'>More...</a></p> This proteome is part of the Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049) pan proteome (fasta)
Buscoi <p>The Benchmarking Universal Single-Copy Ortholog (BUSCO) assessment tool is used, for eukaryotic and bacterial proteomes, to provide quantitative measures of UniProt proteome data completeness in terms of expected gene content. BUSCO scores include percentages of complete (C) single-copy (S) genes, complete (C) duplicated (D) genes, fragmented (F) and missing (F) genes, as well as the total number of orthologous clusters (n) used in the BUSCO assessment.</p> C:99.2%[S:98.4%,D:0.8%],F:0.3%,M:0.5%,n:366 gammaproteobacteria_odb10
Completenessi <p>Complete Proteome Detector (CPD) is an algorithm which employs statistical evaluation of the completeness and quality of proteomes in UniProt, by looking at the sizes of taxonomically close proteomes. Possible values are 'Standard', 'Close to Standard' and 'Outlier'.</p> Close to standard (high value)

Aeromonas salmonicida has been recognized as a pathogen of fish for over 100 years. In 1894 Emmerich and Weibel made the first report of its isolation during a disease outbreak at a Bavarian brown trout hatchery. The manifestations of the disease include furuncle-like swelling and, at a later stage, ulcerative lesions on infected trout. Since that time a number of subspecies of Aeromonas salmonicida have been recognized, although the taxonomy of the species is far from settled. While Aeromonas salmonicida was traditionally thought of as a pathogen of salmonids, global reports now confirm that this pathogen has been associated with clinical or covert disease in a variety of salmonid and non-salmonid species in freshwater, brackish water and sea water.

Aeromonas salmonicida (strain A449) was isolated from a brown trout in the Eure River, France in 1975 and harbors one chromosome and 5 plasmids. Comparison to the related A.hydrophilia ATCC 7966 (AERHH) show the presence of numerous insertion sequence, some of which are still active and various other mobile elements lreading to substantial genome rearrangements. A.salmonicida is no longer mobile and has also recently lost a type IV and type VI secretion systems, thus probably avoiding the host immune system. It seems to be undergoing genome decay and adaptation to its specific host (adapted from PMID 18801193).

Componentsi <p>Genomic components encoding the proteome</p>

Component nameGenome Accession(s)
Component representationProteins
Plasmid pAsa18
Plasmid pAsa27
Plasmid pAsa39
Plasmid pAsa4171
Plasmid pAsa5149


  1. "The genome of Aeromonas salmonicida subsp. salmonicida A449: insights into the evolution of a fish pathogen."
    Reith M.E., Singh R.K., Curtis B., Boyd J.M., Bouevitch A., Kimball J., Munholland J., Murphy C., Sarty D., Williams J., Nash J.H., Johnson S.C., Brown L.L.
    BMC Genomics 9:427-427(2008) [PubMed] [Europe PMC] [Abstract]
  2. "Three small, cryptic plasmids from Aeromonas salmonicida subsp. salmonicida A449."
    Boyd J., Williams J., Curtis B., Kozera C., Singh R., Reith M.
    Plasmid 50:131-144(2003) [PubMed] [Europe PMC] [Abstract]
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