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Stress fiberCytoplasmCytoskeleton


Stress fibers are contractile actomyosin bundles found in non-muscle cells, in eukaryotes, mostly in animals. They are composed of bundles of 10 to 30 actin filaments (microfilaments), crosslinked by alpha-actinin, and non-muscle myosin. They are often anchored to focal adhesions, that connect the extracellular matrix to the actin cytoskeleton. Stress fibers play an essential role in cell contractility, governing cell morphology, adhesion, and migration. In non-motile cells, stress fibers are usually thick and relatively stable. By contrast, highly motile cells typically contain fewer, thinner and more dynamic stress fibers. Stress fibers can be divided into at least 4 different categories : dorsal and ventral stress fibers, transverse arcs and the perinuclear actin cap.


› Cellular component
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