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Graphical

CytoplasmSarcoplasmMyofibril

Definition

A myofibril is a long cylindrical organelle found in muscle cells formed by two transverse filament systems: the thick and thin filaments. The thin filament is composed primarily of actin; it is tethered at one end to the Z-disk, and it interdigitates with the thick filaments. The main constituent of the thick filament is myosin; the direction of the myosin heads changes polarity at the M-line, allowing interaction with the thin filaments anchored from the next adjacent Z-disk. A third and a fourth filament complex exist, comprising the giant proteins titin and nebulin.

Category

› Cellular component

Gene Ontology

More...
GOi

myofibril [ GO:0030016 ]
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