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SynapsePostsynapseNeuron projectionCell junctionCell projectionDendritic spine


A dendritic spine is a small, club-like cell protrusion from neuronal dendrites that form the postsynaptic component of most excitatory synapses in the brain. Spines are complex, dynamic structures that contain a dense array of cytoskeletal, transmembrane, and scaffolding molecules. Despite their modest size, most spines contain at least some form of smooth endoplasmic reticulum, which in the largest spines takes the form of a specialized organelle called the "spine apparatus". These cell protrusions play a critical role in synaptic transmission and plasticity.


Postsynaptic dendritic spine


› Cellular component

Gene Ontology


dendritic spine [ GO:0043197 ]
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