Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Graphical

P-bodyCytoplasmCytoplasmic ribonucleoprotein granule

Definition

P-bodies are dynamic non-membrane bound cytoplasmic structures. These discrete foci function in mRNA decay (decapping and breakdown), RNA-mediated gene silencing (microRNA and siRNA-based gene silencing), mRNA surveillance (or quality control) and translational control. In addition to being sites of mRNA degradation, P-bodies can temporarily sequester mRNAs away from the translation machinery. P-bodies are present in unstressed cells, but are further induced in response to various stresses.

Synonyms

Cytoplasmic mRNA processing body
DCP bodies
Dcp body
Gawky bodies
Gawky body
GW182 bodies
GW182 body
GWB
GW bodies
GW body
mRNA-decay foci
mRNA processing bodies
mRNA processing body
PB
P bodies
P-bodies
P body
Processing bodies
Processing body

Category

› Cellular component

GOi

P-body [ GO:0000932 ]
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again