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Keyword - Immunoglobulin (KW-1280)

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A glycoprotein produced in membrane-bound or secreted form by B lymphocytes. The basic structural unit of an immunoglobulin (Ig) is composed of two identical covalently linked heavy chains and two identical light chains. Both the heavy chains and light chains contain a series of repeating homologous structural units called Ig domains. The N-terminal variable regions of the heavy and light chains form the antigen binding sites, whereas the C-terminal constant regions of the heavy chains interact with other molecules in the immune system. The membrane-bound antibodies serve as receptors that mediate the antigen-triggered activation of B cells. Secreted antibodies function as mediators of specific humoral immunity by engaging various effector mechanisms that serve to eliminate the bound antigen.


  • Antibody


Cellular component

Gene Ontology


immunoglobulin complex [ GO:0019814 ]


ImmunoglobulinImmunityAdaptive immunityCellular componentBiological process
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