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Keyword - Modulation of host virulence by virus (KW-1254)

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Definition

Viral factor that modulates its bacterial host's virulence against a third organism. These virulence factors are mostly expressed from integrated viral genomes and have diverse functions. Bacterial host, and populations, and the encoding (pro)virus probably benefit from the expression of such factors. For example, Bor and Lom outer membrane proteins encoded by bacteriophage lambda modify the virulence of the host bacteria against a eukaryotic target. Some enteric bacterioviruses direct alterations in lipopolysaccharide biosynthesis, resulting in bacterial immune evasion of its eukaryotic target. Other prokaryotic viruses encode exotoxins changing their host bacteria into serious pathogens. A well-known bacterial exotoxin encoded by a provirus is the diphtheria toxin.

Category

Biological process

Gene Ontology

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GOi

modulation of host virulence by virus [ GO:0098676 ]

Graphical

Modulation of host virulence by virusVirulenceBiological process
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