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Keyword - Degradation of host peptidoglycans during virus entry (KW-1236)

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Virion exolysin involved in breaking down host cell peptidoglycans (e.g. murein, pseudomurein) to reach the host cytoplasmic membrane during virus entry. Exolysins are usually part of the tail or the base plate of prokaryotic viruses. Exolysins can display various enzymatic activities such as lysozyme, transglycosylase, muramidase or even protease activity. Murein hydrolases for example are widespread in bacteriophages infecting Gram-positive or Gram-negative bacteria.


Biological process

Gene Ontology


disruption by virus of host cell wall peptidoglycan during virus entry [ GO:0098932 ]


VirionDegradation of host cell envelope components during virus entryDegradation of host peptidoglycans during virus entryVirus entry into host cellCellular componentBiological process
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