Keyword - Modulation of host cell cycle by virus (KW-1121)
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Definition
Viral protein involved in the modulation of host cell cycle. The cell cycle can be divided into four stages: G1, S, G2 and mitosis, while cells resting are termed quiescent cells (G0). Viruses have evolved strategies to modulate cell cycle progression including stimulation of S phase entry from G1 or G0 or cell cycle arrest at G2/M for example. This regulation allows viruses to maximize their own replication.
Category
GOi
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