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Keyword - Inhibition of host mRNA nuclear export by virus (KW-1099)

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Broader

Definition

Viral protein involved in the disruption of the mRNA nuclear export machinery. Viruses have evolved ways of interacting with the nuclear export machinery to inhibit cellular translation and maximize the expression of their own mRNAs. This global inhibition of cellular protein synthesis serves to ensure maximal viral gene expression and to evade host immune response.

Category

Biological process

Gene Ontology

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GOi

suppression by virus of host mRNA export from nucleus [ GO:0039522 ]

Graphical

Host-virus interactionHost gene expression shutoff by virusHost mRNA suppression by virusInhibition of host mRNA nuclear export by virusEukaryotic host gene expression shutoff by virusBiological process
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