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Keyword - Inhibition of host autophagy by virus (KW-1083)

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Broader

Definition

Viral protein involved in the inhibition of host autophagy. Autophagy is a major intracellular pathway in the delivery of cytoplasmic material to lysosomes for degradation. It is also essential for the removal of pathogenic protein aggregates from the cell during infection. Several viruses including influenza and HIV-1 block autophagosome maturation by interacting with and inhibiting host Beclin-1, an essential protein playing a central role in autophagy.

Category

Biological process

Gene Ontology

More...
GOi

suppression by virus of host autophagy [ GO:0039521 ]

Graphical

Host-virus interactionInhibition of host autophagy by virusBiological process
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