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Keyword - Ionotropic glutamate receptor inhibitor (KW-1028)

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Broader

Definition

Protein that inhibits ionotropic glutamate receptor (iGluR). iGluRs are glutamate-gated ion channels that mediate excitatory neurotransmission in the central nervous system. Based on both molecular and pharmacological criteria, iGluRs have been divided into two major classes, the non-NMDA class, which includes both AMPA and kainate subtypes of receptors, and the NMDA class.

Category

Molecular function

Graphical

NeurotoxinToxinIonotropic glutamate receptor inhibitorPostsynaptic neurotoxinMolecular functionIon channel impairing toxin
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