Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Keyword - Suppressor of RNA silencing (KW-0941)


Protein which suppresses host RNA-mediated gene silencing. The most common form of RNA-mediated gene silencing is RNA interference (RNAi), a sequence-specific RNA-degradation mechanism that operates as a natural antiviral system in plants and invertebrates cells. RNAi is mediated by small interfering RNAs (siRNA) of about 21- to 25-nt that target homologous RNAs for destruction. RNA silencing by endogenous micro-RNAs (miRNAs) may also play a role in the antiviral defences of mammals. miRNAs differ from siRNAs in that they generally base pair imperfectly with target RNAs and inhibit their translation by an unknown mechanism.


  • Suppressor of RNAi
  • Suppressor of RNA interference


Molecular function


Molecular functionSuppressor of RNA silencing
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again