Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Keyword - Systemic lupus erythematosus (KW-0772)

Definition

Protein involved in the systemic lupus erythematosus (SLE), a chronic autoimmune disease where the immune system is over-active and produces too many abnormal antibodies that react with the patient's own tissues. The exact cause of lupus is not known, but heredity, environment and hormonal changes may be involved. The immune complex deposition in many tissues leads to the manifestations of the disease. Immune complexes can be deposited in glomeruli, skin, lungs, synovium, mesothelium, and other places. Many SLE patients develop renal complications.

Synonyms

  • SLE

Category

Disease

Graphical

Systemic lupus erythematosusDisease
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again