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Keyword - Signal transduction inhibitor (KW-0734)

Definition

Protein which inhibits signal transduction, the process by which extracellular signals induce intracellular responses. Usually a hormone or neurotransmitter binds to a cell surface receptor which is coupled to a second messenger system, such as that involving cAMP, or to an ion channel. The final downstream consequence of signal transduction is a change in the cell's function, such as a modification in glucose uptake or in cell division. Such a change may be the result of an activation or an inhibition event.

Category

Molecular function

Gene Ontology

More...
GOi

negative regulation of signal transduction [ GO:0009968 ]

Graphical

Molecular functionSignal transduction inhibitor
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