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Keyword - G-protein coupled receptor (KW-0297)

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Receptors which transduce extracellular signals across the cell membrane. At the external side they receive a ligand (a photon in case of opsins), and at the cytosolic side they activate a guanine nucleotide-binding (G) protein. These receptors are hydrophobic proteins that cross the membrane seven times.


  • 7TM receptor
  • GPCR


Molecular function

Gene Ontology


G protein-coupled receptor activity [ GO:0004930 ]
G protein-coupled receptor signaling pathway [ GO:0007186 ]


ReceptorTransducerMolecular functionG-protein coupled receptor
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