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Keyword - DNA-directed RNA polymerase (KW-0240)

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Protein of the DNA-directed RNA polymerase complexes, which catalyze RNA synthesis the by addition of ribonucleotide units to a RNA chain using DNA as a template. They can initiate a chain de novo. Prokaryotes have a single enzyme for the three RNA types that is subject to stringent regulatory mechanisms. Eukaryotes have type I that synthesizes all rRNA except the 5S component, type II that synthesizes mRNA and hnRNA and type III that synthesizes tRNA and the 5S component of rRNA.


Cellular component

Gene Ontology


DNA-directed 5'-3' RNA polymerase activity [ GO:0003899 ]


DNA-directed RNA polymeraseTranscriptionCellular componentBiological process
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