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Keyword - Mast cell degranulation (KW-0467)


Protein involved in mast cell degranulation. Mast cell is a large, ovoid cell of hematopoietic lineage, with a centrally located nucleus and numerous large, intensely basophilic granules. The binding of an antigen to its specific immunoglobulin-E antibody on the mast cell surface triggers the release of the MC granules. Mast cells are involved in hypersensitivity reactions.


Biological process

Gene Ontology


mast cell degranulation [ GO:0043303 ]


Mast cell degranulationBiological process
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