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Keyword - Syncytium formation induced by viral infection (KW-1180)


Viral protein that mediates fusion of an infected cell with neighboring cells leading to the formation of multi-nucleate enlarged cells called syncytia. Usually these syncytia are the result of expression of a viral fusion protein at the host cell membrane during viral replication. Viruses such as herpesviruses are known to induce the formation of syncytia.


  • Induction by virus of host cell-cell fusion
  • Polykaryons formation in virally infected cells


Biological process

Gene Ontology


positive regulation of syncytium formation by virus [ GO:0060141 ]


Syncytium formation induced by viral infectionBiological process
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