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Keyword - Inhibition of host MHC class I molecule presentation by virus (KW-1115)

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Broader

Definition

Viral protein involved in the evasion of host adaptive immune response by inhibiting the presentation of loaded MHC class I molecules at the cell surface. Many viruses 'intercept' the loaded MHC class I molecules and retain them in the endoplasmic reticulum or target them to degradation in order to prevent presentation of the peptides at the cell surface.

Category

Biological process

Gene Ontology

More...
GOi

suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I [ GO:0046776 ]

Graphical

Host-virus interactionViral immunoevasionInhibition of host adaptive immune response by virusInhibition of host MHC class I molecule presentation by virusBiological process
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