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Keyword - Inhibition of host RNA polymerase II by virus (KW-1104)

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Viral protein involved in the disruption of the host RNA polymerase II. Many viruses induce alterations in the cellular gene expression. Among these, shutoff of host transcription by targeting RNA polymerase II is commonly used. Indeed, many viruses are able to modify RNAP II CTD including Herpes virus, HIV, Epstein-Barr virus or Bunyamwera virus.


Biological process

Gene Ontology


suppression by virus of host RNA polymerase II activity [ GO:0039523 ]


Inhibition of host RNA polymerase II by virusHost-virus interactionHost gene expression shutoff by virusEukaryotic host transcription shutoff by virusEukaryotic host gene expression shutoff by virusBiological process
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