Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Keyword - Inhibition of host RIG-I by virus (KW-1088)

Keywords navigation



Viral protein involved in the evasion of host innate defense by inhibiting the DDX58/RIG-I protein. Upon recognition of viral RNA, the cytosolic receptor DDX58/RIG-I initiates an antiviral signaling cascade by interacting with downstream partners. Several viral proteins inhibit DDX58/RIG-I via direct interaction while others via proteolytic cleavage.


Biological process

Gene Ontology


suppression by virus of host RIG-I activity [ GO:0039540 ]


Inhibition of host RIG-I by virusHost-virus interactionInhibition of host innate immune response by virusViral immunoevasionInhibition of host RLR pathway by virusBiological process
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again